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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1893 Results for "
prokaryotic homolog
" in MedChemExpress (MCE) Product Catalog:
Products (1893)
1893 Results for "prokaryotic homolog" in MCE Product Catalog:
71
71 Publications Verification
Cat. No.: HY-108718
CAS No.: 49863-47-0
Synonyms: Geneticin; Antibiotic G-418
Target:
Research Areas:
G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .
43
Target:
Research Areas:
Sotuletinib (BLZ945) is a potent, selective, orally active and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. Sotuletinib can be used for microglia depletion, and for tumor and CNS-related disease research .
43
43 Cited Publications
Synonyms: BLZ945 hydrochloride
Sotuletinib (BLZ945) hydrochloride is a potent, selective, orally active and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. Sotuletinib hydrochloride can be used for microglia depletion, and for tumor and CNS-related disease research. .
42
42 Cited Publications
Target:
Research Areas:
BRM/BRG1 ATP Inhibitor-1 (compound 14) is an orally active allosteric dual brahma homolog (BRM)/SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2 (SMARCA2) and brahma related gene 1 (BRG1)/SMARCA4 ATPase activity inhibitor, both IC50s are below 0.005 µM. BRM/BRG1 ATP Inhibitor-1 has anticancer activity .
41
Category:
Antifungal Disease Research Antibacterial Other Antibiotics Infection Microorganisms Plant Cell Culture Antibiotics Resistance Selection Disease Research Fields
Target:
22
22 Cited Publications
Target:
Research Areas:
SF1670 is a potent and specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor .
18
11
11 Cited Publications
Cat. No.: HY-P7155A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DKK1; Dickkopf 1 homolog (Xenopus Laevis); Dickkopf Wnt Signaling Pathway Inhibitor 1; Dickkopf 1 homolog; SK; Dickkopf-1 Like; DKK-1; Dickkopf-1; Dickkopf-Related Protein 1; HDkk-1; Dickkopf-Like Protein 1; Dkk-1; Dickkopf (Xenopus Laevis) homolog 1
Species:
Human
Source:
HEK293
10
10 Cited Publications
Cat. No.: HY-P73361
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 Ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; Programmed Cell Death 1 Ligand 1; Programmed Death Ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:
Human
Source:
HEK293
9
9 Cited Publications
Cat. No.: HY-K1056
MCE G418 Selective Antibiotic, Sterile (50 mg/mL) is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.
8
8 Cited Publications
GNE-7883 is a pan-TEAD inhibitor that blocks the association of YAP/TAZ with TEAD. GNE-7883 effectively reduces chromatin accessibility at TEAD motifs, inhibits cell proliferation in multiple cell line models, and achieves strong anti-tumor efficacy in vivo. In addition, GNE-7883 effectively overcomes intrinsic and acquired resistance to KRAS (Kirsten rat sarcoma viral oncogene homolog) G12C inhibitors in multiple preclinical models by inhibiting YAP/TAZ activation .
7
7 Cited Publications
Cat. No.: HY-P70704
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LEP; Leptin (Murine Obesity homolog); Prev. OBS; Obese Protein; Prev. OB; Obese, Mouse, homolog Of; Obesity Factor; LEPD; Leptin; Leptin (Obesity homolog, Mouse)
Species:
Mouse
Source:
E. coli
6
6 Cited Publications
Cat. No.: HY-P7154
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DKK1; Dickkopf 1 homolog (Xenopus Laevis); Dickkopf Wnt Signaling Pathway Inhibitor 1; Dickkopf 1 homolog; SK; Dickkopf-1 Like; DKK-1; Dickkopf-1; Dickkopf-Related Protein 1; HDkk-1; Dickkopf-Like Protein 1; Dkk-1; Dickkopf (Xenopus Laevis) homolog 1
Species:
Mouse
Source:
CHO
5
Target:
Research Areas:
ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist with an IC50 of 3.7 μM. ML-180 is inactive for steroidogenic factor-1 (SF-1; NR5A1; IC50>10 μM). ML-180 has the potential for LRH-1-dependent cancers .
5
5 Cited Publications
Cat. No.: HY-P71323
Purity: ≥85%, as determined by reducing SDS-PAGE.
Synonyms: SMAD3; MAD, Mothers Against Decapentaplegic homolog 3; Prev. MADH3; SMAD, Mothers Against DPP homolog 3; JV15-2; SMA- And MAD-Related Protein 3; HsT17436; Mothers Against DPP homolog; Mothers Against Decapentaplegic homolog 3; Mad Protein homolog; Mothers Against DPP homolog 3; Mad homolog JV15-2; MAD homolog 3; SMAD Family Member; HMAD-3; MAD homolog; HSMAD3; HSPC193; Mad3; SMAD 3; MAD, Mothers Against Decapentaplegic homolog 3 (Drosophila); LDS1C; SMAD, Mothers Against DPP homolog 3 (Drosophila); LDS3; SMAD Family Member 3; Mothers Against Decapentaplegic homolog
Species:
Human
Source:
E. coli
5
5 Cited Publications
Cat. No.: HY-P71596
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SIRT1; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, homolog) 1; Sirtuin 1; Sirtuin (Silent Mating Type Information Regulation 2 homolog) 1 (S. Cerevisiae); SIR2L1; Protein Acetyllysine N-Acetyltransferase; NAD-Dependent Protein Dea
Species:
Human
Source:
E. coli
5
5
5 Cited Publications
Cat. No.: HY-P72968
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DKK1; Dickkopf 1 homolog (Xenopus Laevis); Dickkopf Wnt Signaling Pathway Inhibitor 1; Dickkopf 1 homolog; SK; Dickkopf-1 Like; DKK-1; Dickkopf-1; Dickkopf-Related Protein 1; HDkk-1; Dickkopf-Like Protein 1; Dkk-1; Dickkopf (Xenopus Laevis) homolog 1
Species:
Human
Source:
HEK293
5
5 Cited Publications
Cat. No.: HY-P75841
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: IL18BP; MC51L-53L-54L homolog Gene Product; Interleukin 18 Binding Protein; Tadekinig-Alfa; Interleukin-18-Binding Protein; IL-18BP; IL18BPa; FVH
Species:
Mouse
Source:
HEK293
4
4 Cited Publications
Cat. No.: HY-P80853
Synonyms: SMAD2; MADH2; MADR2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
