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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
synaptosomal
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "synaptosomal" in MCE Product Catalog:
1
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Lyso-PAF C-16 is a precursor and metabolite of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (PAF C-16). Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase .
Cat. No.: HY-N6745
CAS No.: 25425-12-1
Category:
Cardiovascular Disease Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-124030
CAS No.: 70030-11-4
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3-Hydroxyphenazepam is an active metabolite of Cinazepam. Cinazepam is a GABAA receptor agonist. 3-Hydroxyphenazepam can inhibit synaptosomal transporter-mediated [ 3H]GABA uptake .
Cat. No.: HY-NP180
Cat. No.: HY-106407
CAS No.: 135928-30-2
Synonyms: Org 4428; ADL 6906
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Beloxepin (Org 4428) is an orally active synaptosomal noradrenalin reuptake inhibitor and a 5-HT2 receptor antagonist. Beloxepin shows about 100-fold less affine for other monoamine carriers. Beloxepin has antidepressant and pain-relieving effects .
Cat. No.: HY-P3071
CAS No.: 172450-46-3
Synonyms: Stichodactyla helianthus neurotoxin
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Cat. No.: HY-W127407
CAS No.: 201738-25-2
Cat. No.: HY-131527R
CAS No.: 93413-90-2
Synonyms: N-Desmethyl Venlafaxine hydrochloride (Standard); Wy 45494 (Standard)
Research Areas:
Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride). This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively). In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.
Synonyms: Lyso-platelet-activating factor C-16-d4
Cat. No.: HY-P11029
Cat. No.: HY-117251
CAS No.: 1142050-84-7
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LP-403812 is a high affinity proline transporter (PROT) inhibitor that produces dose-dependent inhibition of hPROT (IC50=0.11 μM; Ki=0.12 μM) and also inhibits the activity of mouse brain synaptosomal mPROT with the same potency (IC50=0.23 μM). LP-403812 can be used to study the function of PROT in the brain .
Cat. No.: HY-P3071A
Synonyms: Stichodactyla helianthus neurotoxin TFA
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Cat. No.: HY-110016
CAS No.: 150314-35-5
Synonyms: DEA
Cat. No.: HY-141581S
Cat. No.: HY-105521A
CAS No.: 94096-42-1
Synonyms: (S)-Nafenodone; LU-43706
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Dexnafenodone hydrochloride ((S)-Nafenodone) as an antidepressant compound, is a potent and selective inhibitor of the synaptosomal uptake of noradrenaline, but has a less potent effect on serotonin uptake and a negligible effect on dopamine uptake.
Cat. No.: HY-114040
CAS No.: 159094-94-7
Synonyms: NNC-711 free acid
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NO-711 (NNC-711) free acid is a novel potent and selective inhibitor of γ-aminobutyric acid uptake. NO-711 inhibits synaptosomal (IC50 = 47 nM), neuronal (IC50 = 1238 nM) and glial (IC50 = 636 nM) GABA uptake in vitro .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
