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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
116 Results for "
umbilical vein endothelial cells
" in MedChemExpress (MCE) Product Catalog:
Products (116)
116 Results for "umbilical vein endothelial cells" in MCE Product Catalog:
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8 Publications Verification
Cat. No.: HY-19765
CAS No.: 1419609-94-1
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GSK2798745 is a potent, selective, and orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker with IC50s of 1.8 and 1.6 nM for hTRPV4 and rTRPV4, respectively. GSK2798745 can be used in cardiac and respiratory diseases research .
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Tricarbonyldichlororuthenium(II) dimer (CORM-2) is a CO-releasing molecule. Tricarbonyldichlororuthenium(II) dimer exhibits anti-inflammatory, antioxidant, and gastric mucosa-protective activities. Additionally, Tricarbonyldichlororuthenium(II) dimer has CO-independent functional effects on multiple potassium channels .
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4 Cited Publications
Cat. No.: HY-N2445
CAS No.: 37308-75-1
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3 Cited Publications
Synonyms: L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid
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2 Cited Publications
Cat. No.: HY-N0515
CAS No.: 945619-74-9
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1 Cited Publications
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NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity . NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase with IC50 values of 17 nM and 20 nM . NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells with an IC50 of 30 nM . NS-2028 is commonly used in the research of nitric oxide signaling pathways, it inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM) . NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability .
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Cardiovascular Disease Neurological Disease Plants Infection Alkaloids Capsicum annuum L. Other Alkaloids Solanaceae Disease Research Fields Inflammation/Immunology
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1 Cited Publications
Cat. No.: HY-W036410
CAS No.: 13822-56-5
Synonyms: 3-Aminopropyltrimethoxysilane; APTMS
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Aminopropyltrimethoxysilane (3-Aminopropyltrimethoxysilane; APTMS) is an aminosilane coupling agent and self-assembled molecule that can form self-assembled monolayers or multilayers on the surfaces of silicon-based materials, platinum, pullulan (Viscosity (10%): 15-180 mPa.s) (HY-W145522), and magnesium alloys through silanization or amine-mediated adsorption, serving for surface functionalization and performance regulation. Aminopropyltrimethoxysilane is applicable in research related to biomedical materials, antibacterial materials, and corrosion protection .
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1 Cited Publications
Cat. No.: HY-Y0319B1
CAS No.: 127-08-2
Cat. No.: HY-P991202
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Cat. No.: HY-P5282
CAS No.: 221882-20-8
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Infection Neurological Disease Inflammation/Immunology Cancer
Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 (COX-1)/cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-κB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimer’s disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimer’s disease .
Cat. No.: HY-W588250
CAS No.: 24730-31-2
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Cat. No.: HY-B0862
CAS No.: 40487-42-1
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Environmental Pollutants Herbicide Apoptosis Bcl-2 Family Caspase SOD Mitochondrial Metabolism
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Pendimethalin is an orally active herbicide that controls annual grasses and certain broadleaf weeds. Pendimethalin induces Apoptotic cell death through activating ER stress-mediated mitochondrial dysfunction in human umbilical vein endothelial cells .
Cat. No.: HY-N2055
CAS No.: 19895-95-5
Cat. No.: HY-P3522
CAS No.: 107978-83-6
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Cat. No.: HY-P5558
CAS No.: 917760-16-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
