SIRT1-IN-4
Based on 1 Customer Validation
SIRT1-IN-4 (Compound 8c) is a SIRT1 inhibitor, with an IC50 of 10.04 μM. SIRT1-IN-4 can be used for the research of cancer.
For research use only. We do not sell to patients.
- Purity: 98.62%
- CAS No.: 445405-18-5
- Formula: C25H18O7
- Molecular Weight:430.41
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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SIRT1 10.04 μM (IC50) |
Chemical Information
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CAS No. 445405-18-5
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Appearance Solid
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Molecular Weight 430.41
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Formula C25H18O7
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Color White to off-white
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SMILES
O=C(C1=CC=CC(COC2=CC=C(/C=C3C(OC(C4=CC=CC=C4)OC\3=O)=O)C=C2)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (232.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3234 mL | 11.6168 mL | 23.2337 mL | 58.0842 mL |
| 5 mM | 0.4647 mL | 2.3234 mL | 4.6467 mL | 11.6168 mL | |
| 10 mM | 0.2323 mL | 1.1617 mL | 2.3234 mL | 5.8084 mL | |
| 15 mM | 0.1549 mL | 0.7745 mL | 1.5489 mL | 3.8723 mL | |
| 20 mM | 0.1162 mL | 0.5808 mL | 1.1617 mL | 2.9042 mL | |
| 25 mM | 0.0929 mL | 0.4647 mL | 0.9293 mL | 2.3234 mL | |
| 30 mM | 0.0774 mL | 0.3872 mL | 0.7745 mL | 1.9361 mL | |
| 40 mM | 0.0581 mL | 0.2904 mL | 0.5808 mL | 1.4521 mL | |
| 50 mM | 0.0465 mL | 0.2323 mL | 0.4647 mL | 1.1617 mL | |
| 60 mM | 0.0387 mL | 0.1936 mL | 0.3872 mL | 0.9681 mL | |
| 80 mM | 0.0290 mL | 0.1452 mL | 0.2904 mL | 0.7261 mL | |
| 100 mM | 0.0232 mL | 0.1162 mL | 0.2323 mL | 0.5808 mL |