Sulfamethoxazole-NO
Based on 1 Customer Validation
Sulfamethoxazole-NO (SMX-NO) is the major immunogen in sulfonamide allergy, producing modest ascorbic acid depletion and hemoglobin adduct formation. Sulfamethoxazole-NO haptens tissue proteins and is immunogenic in rodents.
For research use only. We do not sell to patients.
- CAS No.: 29699-89-6
- Formula: C10H9N3O5S
- Molecular Weight:283.26
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| J774 | IC50 |
>256 μM
Compound: 4Da
|
Cytotoxicity against mouse J774 cells after 24 hrs by by resazurin reduction test
Cytotoxicity against mouse J774 cells after 24 hrs by by resazurin reduction test
|
[PMID: 19811921] |
Chemical Information
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CAS No. 29699-89-6
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Appearance Solid
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Molecular Weight 283.26
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Formula C10H9N3O5S
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Color White to off-white
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SMILES
O=S(C1=CC=C([N+]([O-])=O)C=C1)(NC2=NOC(C)=C2)=O
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Synonyms
SMX-NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (353.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5303 mL | 17.6516 mL | 35.3033 mL | 88.2581 mL |
| 5 mM | 0.7061 mL | 3.5303 mL | 7.0607 mL | 17.6516 mL | |
| 10 mM | 0.3530 mL | 1.7652 mL | 3.5303 mL | 8.8258 mL | |
| 15 mM | 0.2354 mL | 1.1768 mL | 2.3536 mL | 5.8839 mL | |
| 20 mM | 0.1765 mL | 0.8826 mL | 1.7652 mL | 4.4129 mL | |
| 25 mM | 0.1412 mL | 0.7061 mL | 1.4121 mL | 3.5303 mL | |
| 30 mM | 0.1177 mL | 0.5884 mL | 1.1768 mL | 2.9419 mL | |
| 40 mM | 0.0883 mL | 0.4413 mL | 0.8826 mL | 2.2065 mL | |
| 50 mM | 0.0706 mL | 0.3530 mL | 0.7061 mL | 1.7652 mL | |
| 60 mM | 0.0588 mL | 0.2942 mL | 0.5884 mL | 1.4710 mL | |
| 80 mM | 0.0441 mL | 0.2206 mL | 0.4413 mL | 1.1032 mL | |
| 100 mM | 0.0353 mL | 0.1765 mL | 0.3530 mL | 0.8826 mL |