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Sulfuretin 

Cat. No.: HY-N1193
Handling Instructions

Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM.

For research use only. We do not sell to patients.

Sulfuretin Chemical Structure

Sulfuretin Chemical Structure

CAS No. : 120-05-8

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Description

Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].

In Vitro

Sulfuretin is one of the main flavonoids produced by Rhus verniciflua. Sulfuretin efficiently inhibits the infiltration of inflammatory cells and attenuates allergic airway inflammation.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Pathogen-free male BALB/c mice (7-8 weeks old)[1]
Dosage: 40 μg/kg
Administration: A single intraperitoneal injection was administered 2 h after the last OVA challenge
Result: Suppressed OVA-induced chemotaxis and airway inflammation.
Molecular Weight

270.24

Formula

C₁₅H₁₀O₅

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Sulfuretin
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