TK4g
TK4g is a Janus kinase (JAK) inhibitor with the IC50 values of 12.61 nM and 15.80 nM for JAK2 and JAK3, respectively. TK4g can be used in lymphoid-derived diseases and leukemia cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2232890-86-5
- Formula: C19H19N3O4S
- Molecular Weight:385.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
JAK2 12.61 nM (IC50) |
JAK3 15.80 nM (IC50) |
Chemical Information
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CAS No. 2232890-86-5
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Molecular Weight 385.44
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Formula C19H19N3O4S
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SMILES
O=S(C1=CC=CC(N2N(CC)C(C)=C(C(C3=CC=CC=C3)=O)C2=O)=C1)(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TK4g Related Classifications
HY-151258 Related Classifications
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