Tolafentrine
Tolafentrine, a dual-selective phosphodiesterase 3/4 (PDE3/4) inhibitor, has been shown to have significant acute and chronic effects in a unilateral diacetamide-induced rat pulmonary hypertension model. Experiments show that long-term administration can significantly alleviate all unilateral bisacetamide-induced hemodynamic and gas exchange abnormalities, reduce right ventricular hypertrophy, and normalize pulmonary vascular remodeling changes.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 139308-65-9
- Fòrmula: C28H31N3O4S
- Peso molecular:505.63
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
-
No. CAS 139308-65-9
-
Peso molecular 505.63
-
Fòrmula C28H31N3O4S
-
SMILES
[H][C@@]12CN(CC[C@@]1(N=C(C3=C2C=C(C(OC)=C3)OC)C4=CC=C(C=C4)NS(C5=CC=C(C=C5)C)(=O)=O)[H])C
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)