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CLM3

CLM3, a pyrazolopyrimidine derivative, is a multiple tyrosine kinase inhibitor. CLM3 shows antiproliferative and proapoptotic activity on endothelial and cancer cells, synergistically enhanced by SN38 (HY-13704). These effects are mainly due to its inhibition of phosphorylation of VEGFR-2, EGFR and RET tyrosine kinases and their related signaling pathways.

For research use only. We do not sell to patients.

  • CAS No.: 1312024-59-1
  • Formula: C21H21N5
  • Molecular Weight:343.42
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • CLM3 Chemical Structure
    CLM3 Chemical Structure
CAS No.: 1312024-59-1
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Use of MCE Products

All VEGFR Isoforms

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All EGFR Isoforms

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  • CLM3 Chemical Structure
    CLM3 Chemical Structure
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  • CLM3