Tyk2-IN-20
Tyk2-IN-20 (Example 289) is a potent Tyk2 inhibitor with an IC50 of <5 nM. Tyk2-IN-20 als inhibits JAK1, JAK2, and JAK3 with IIC50 values of <100 nM. Tyk2-IN-20 can be used for the study of inflammatory diseases.
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- CAS. Nr.: 3058568-08-1
- Formel: C24H25N7O2
- Molecular Weight:443.50
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Tyk2 <5 nM (IC50) |
JAK1 <100 nM (IC50) |
JAK2 <100 nM (IC50) |
JAK3 <100 nM (IC50) |
Chemical Information
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CAS. Nr. 3058568-08-1
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Molecular Weight 443.50
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Formel C24H25N7O2
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SMILES
C[C@@H]([C@@](C#N)(C1CC1)C2=O)CN2C3=NC(C4=CN(C5CC6(COC6)C5)N=C4)=CN7C3=CC=N7
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Tyk2-IN-20 Related Classifications
HY-168269 Related Classifications
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