Tyk2-IN-20
Tyk2-IN-20 (Example 289) is a potent Tyk2 inhibitor with an IC50 of <5 nM. Tyk2-IN-20 als inhibits JAK1, JAK2, and JAK3 with IIC50 values of <100 nM. Tyk2-IN-20 can be used for the study of inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 3058568-08-1
- Formula: C24H25N7O2
- Molecular Weight:443.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Tyk2 <5 nM (IC50) |
JAK1 <100 nM (IC50) |
JAK2 <100 nM (IC50) |
JAK3 <100 nM (IC50) |
Chemical Information
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CAS No. 3058568-08-1
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Molecular Weight 443.50
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Formula C24H25N7O2
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SMILES
C[C@@H]([C@@](C#N)(C1CC1)C2=O)CN2C3=NC(C4=CN(C5CC6(COC6)C5)N=C4)=CN7C3=CC=N7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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