UCHL1-IN-1
Based on 1 Customer Validation
UCHL1-IN-1 (Compound 46) is an inhibitor for Ubiquitin C-terminal Hydrolase L1 (UCHL1), with an IC50 of 5.1 μM. UCHL1-IN-1 can be used for cancer research.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 3068994-24-8
- Formula: C11H13Cl2N3O2
- Molecular Weight:290.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
UCHL1 |
In Vitro
UCHL1-IN-1 (0-50 μM, 4 h) inhibits UCHL1 in BT549 cell[1].
UCHL1-IN-1 (0-50 μM, 24 h) inhibits cell migration and cell viability in BT549 cell[1].
UCHL1-IN-1 is relatively metabolically stable in human liver microsomes assay, with a t1/2 > 120 min, and low intrinsic hepatic clearance[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 3068994-24-8
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Appearance Solid
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Molecular Weight 290.15
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Formula C11H13Cl2N3O2
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Color White to off-white
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SMILES
ClCC(NNC(CN(C1=CC=C(C=C1)Cl)C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UCHL1-IN-1 Related Classifications
HY-161378 Related Classifications
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