2. Cell Cycle/DNA Damage
  3. Deubiquitinase
  4. UCHL1-IN-1

UCHL1-IN-1 (Compound 46) is an inhibitor for Ubiquitin C-terminal Hydrolase L1 (UCHL1), with an IC50 of 5.1 μM. UCHL1-IN-1 can be used for cancer research.

For research use only. We do not sell to patients.

UCHL1-IN-1 Chemical Structure

UCHL1-IN-1 Chemical Structure

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UCHL1-IN-1 Related Antibodies

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Description

UCHL1-IN-1 (Compound 46) is an inhibitor for Ubiquitin C-terminal Hydrolase L1 (UCHL1), with an IC50 of 5.1 μM. UCHL1-IN-1 can be used for cancer research[1].

IC50 & Target[1]

UCHL1

 

In Vitro

UCHL1-IN-1 (0-50 μM, 4 h) inhibits UCHL1 in BT549 cell[1].
UCHL1-IN-1 (0-50 μM, 24 h) inhibits cell migration and cell viability in BT549 cell[1].
UCHL1-IN-1 is relatively metabolically stable in human liver microsomes assay, with a t1/2 > 120 min, and low intrinsic hepatic clearance[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UCHL1-IN-1 Related Antibodies
Molecular Weight

290.15

Formula

C11H13Cl2N3O2
SMILES

ClCC(NNC(CN(C1=CC=C(C=C1)Cl)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UCHL1-IN-1 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UCHL1-IN-1DeubiquitinaseDUBsBT549cell migrationInhibitorinhibitorinhibit

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