Sahandol
Sahandol is a diterpene, that can be isolated from Salvia sahendica. Sahandol shows antiplasmodial, antitrypanosomal, and cytotoxic activities.
For research use only. We do not sell to patients.
- CAS No.: 1452398-07-0
- Formula: C20H24O2
- Molecular Weight:296.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Biological Activity
Description
In Vitro
Sahandol shows activity against P. falciparum K1, T. brucei rhodesiense STIB 900, and L6-cells, with IC50 values of 1.3 ± 0.3 μM, 2.9 ± 0.1 μM, and 0.2 ± 0.1 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1452398-07-0
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Molecular Weight 296.40
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Formula C20H24O2
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SMILES
OC1=C2C(C(C[C@H](/C=C(C)\C)O2)=C(C)C=C3)=C3C=C1C(C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sahandol Related Classifications
HY-N8476 Related Classifications
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