2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. Usnoflast

Usnoflast is a NLRP3 modulator, as well as a non-steroidal anti-inflammatory agent (NSAD).

For research use only. We do not sell to patients.

Usnoflast Chemical Structure

Usnoflast Chemical Structure

CAS No. : 2455519-86-3

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1 mg USD 450 In-stock
5 mg USD 1150 In-stock
10 mg USD 1880 In-stock
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Based on 1 publication(s) in Google Scholar

Usnoflast Related Antibodies

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Description

Usnoflast is a NLRP3 modulator, as well as a non-steroidal anti-inflammatory agent (NSAD)[1].

IC50 & Target

NLRP3[1]
Molecular Weight

403.54

Formula

C21H29N3O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]1(N(CCC1)C)/C=C/S(NC(NC2=C3C(CCC3)=CC4=C2CCC4)=O)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (154.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4781 mL 12.3903 mL 24.7807 mL
5 mM 0.4956 mL 2.4781 mL 4.9561 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4781 mL 12.3903 mL 24.7807 mL 61.9517 mL
5 mM 0.4956 mL 2.4781 mL 4.9561 mL 12.3903 mL
10 mM 0.2478 mL 1.2390 mL 2.4781 mL 6.1952 mL
15 mM 0.1652 mL 0.8260 mL 1.6520 mL 4.1301 mL
20 mM 0.1239 mL 0.6195 mL 1.2390 mL 3.0976 mL
25 mM 0.0991 mL 0.4956 mL 0.9912 mL 2.4781 mL
30 mM 0.0826 mL 0.4130 mL 0.8260 mL 2.0651 mL
40 mM 0.0620 mL 0.3098 mL 0.6195 mL 1.5488 mL
50 mM 0.0496 mL 0.2478 mL 0.4956 mL 1.2390 mL
60 mM 0.0413 mL 0.2065 mL 0.4130 mL 1.0325 mL
80 mM 0.0310 mL 0.1549 mL 0.3098 mL 0.7744 mL
100 mM 0.0248 mL 0.1239 mL 0.2478 mL 0.6195 mL
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Usnoflast Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Usnoflast2455519-86-3NOD-like Receptor (NLR)Inhibitorinhibitorinhibit

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