USP1-IN-4
USP1-IN-4 (compound 10) is an effective USP1 inhibitor with an IC50 value of 2.44 nM. USP1-IN-4 has anticancer activity and synergistic activity with various anticancer drugs.
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- CAS No.: 2878441-72-4
- Formule: C26H23F3N6
- Masse moléculaire:476.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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USP1 2.44 nM (IC50) |
In Vitro
USP1-IN-4 (0.0005-10 μM, 15 min) inhibits USP1/UAF1 significantly with an IC50 value of 2.44 nM[1].
USP1-IN-4 (0.0005-10 μM, 7 days) inhibits the growth of MDA-MB-436 significantly with an IC50 value of 103.75 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MDA-MB-436
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Concentration:0.0005-10 μM
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Incubation Time:7 days
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Result:Inhibited cell growth with an IC50 of 103.75 nM.
Chemical Information
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CAS No. 2878441-72-4
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Masse moléculaire 476.50
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Formule C26H23F3N6
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SMILES
FC(F)(C1=CN(C)C(C2=CC=C(CC3=NC=C4C=NC(C5=C(C(C)C)C=CC=C5)=NN43)C=C2)=N1)F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
USP1-IN-4 Related Classifications
HY-153731 Related Classifications
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