2. Immunology/Inflammation
  3. COX
  4. Valeryl salicylate

Valeryl salicylate  (Synonyms: Valeroyl salicylate)

Cat. No.: HY-128473 Purity: ≥99.0%
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Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect.

For research use only. We do not sell to patients.

Valeryl salicylate Chemical Structure

Valeryl salicylate Chemical Structure

CAS No. : 64206-54-8

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Based on 1 publication(s) in Google Scholar

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Description

Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1].

IC50 & Target[1]

COX-1

 

In Vivo

Valeryl salicylate (3, 10, 30 mg/kg; i.p.) shows anti-inflammatory effect in arachidonic acid (HY-109590)-induced ear oedema and Carrageenan (HY-125474)-induced paw oedema[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 25-30g, Swiss male mice (arachidonic acid induces Ear oedema)[1]
Dosage: 1.5, 4.5, 15, 45 μg per ear
Administration:
Result: Showed the anti-inflammatory effect of topical administration and resulted in significant inhibition of the ear oedema of28, 36, 40, and 58% at 1.5, 4.5, 15, 45 μg per ear.
Animal Model: 25-30g, Swiss male mice (Carrageenan-induced paw oedema)[1]
Dosage: 3, 10, 30 mg/kg
Administration: I.p.
Result: Promoted a significant inhibition of 43.3, 53.3 and 66.6% at 3, 10, 30 mg/kg, respectively.
Molecular Weight

222.24

Formula

C12H14O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=CC=C1OC(CCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

COA (247 KB)

Handling Instructions (2659 KB)
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Valeryl salicylate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Valeryl64206-54-8ValeroylCOXCyclooxygenaseanti-inflammatoryarachidonic acidCarrageenanoedemaInhibitorinhibitorinhibit

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