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WRN-IN-19

WRN-IN-19 (Compound (S)-27) is a covalent WRN helicase inhibitor, with pIC50 (0 h/4 h) = 5.4/7.5 in the DNA-unwinding 5 endpoint assays. WRN-IN-19 shows synthetic lethality in MSI-H (high microsatellite instability) cancer cells.

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  • CAS No.: 3058652-58-4
  • Formula: C23H26F3N3O3
  • Molecular Weight:449.47
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • WRN-IN-19 Chemical Structure
    WRN-IN-19 Chemical Structure
CAS No.: 3058652-58-4
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All DNA/RNA Synthesis Isoforms

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  • WRN-IN-19 Chemical Structure
    WRN-IN-19 Chemical Structure
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  • WRN-IN-19