XMD-17-51
Based on 1 publication(s) in Google Scholar
XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases.
For research use only. We do not sell to patients.
- CAS No.: 1628614-50-5
- Formula: C21H24N8O
- Molecular Weight:404.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) XMD-17-51
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Biological Activity
XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), polo kinase 1, 2, 3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK, ULK2, PLK, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and can be used in the treatment of various diseases, disorders or conditions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1628614-50-5
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Molecular Weight 404.47
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Formula C21H24N8O
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SMILES
O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Front Pharmacol
2021 Mar 8:12:603453. PMID: 33762936
Purity & Documentation
References
[1]. WO 2014145909 A2.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)