β-Caryophyllene-d2
Based on 1 Customer Validation
β-Caryophyllene-d2 is deuterium labeled β-Caryophyllene. β-Caryophyllene is a CB2 receptor agonist.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 94.21%
- CAS No.: 2006272-96-2
- Formule: C15H22D2
- Masse moléculaire:206.36
-
Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
-
Solvant et solubilité
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Endogenous Metabolite
More
Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2006272-96-2
-
Unlabeled CAS 87-44-5
-
Appearance Oil
-
Masse moléculaire 206.36
-
Formule C15H22D2
-
Color Colorless to light yellow
-
SMILES
CC1([C@@]2([H])[C@](/C(CC/C=C(CC2)/C)=C([2H])\[2H])([H])C1)C
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
Ethanol : ≥ 176.67 mg/mL (856.13 mM)
DMSO : 50 mg/mL (242.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 0.67 mg/mL (3.25 mM; Need ultrasonic)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
-
Fiche technique (277 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Instruction de manipulation (2659 KB)
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Cheng Y, et al. β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway. Pharmacology. 2014;94(1-2):1-12. [Content Brief]
[3]. Dahham SS, et al. The Anticancer, Antioxidant and Antimicrobial Properties of the Sesquiterpene β-Caryophyllenefrom the Essential Oil of Aquilaria crassna. Molecules. 2015 Jun 26;20(7):11808-29. [Content Brief]
[4]. de Oliveira CC, et al. Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures. Epilepsy Behav. 2016 Mar;56:26-31. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO / Ethanol | 1 mM | 4.8459 mL | 24.2295 mL | 48.4590 mL | 121.1475 mL |
| DMSO / Ethanol | 5 mM | 0.9692 mL | 4.8459 mL | 9.6918 mL | 24.2295 mL |
| 10 mM | 0.4846 mL | 2.4230 mL | 4.8459 mL | 12.1148 mL | |
| 15 mM | 0.3231 mL | 1.6153 mL | 3.2306 mL | 8.0765 mL | |
| 20 mM | 0.2423 mL | 1.2115 mL | 2.4230 mL | 6.0574 mL | |
| 25 mM | 0.1938 mL | 0.9692 mL | 1.9384 mL | 4.8459 mL | |
| 30 mM | 0.1615 mL | 0.8077 mL | 1.6153 mL | 4.0383 mL | |
| 40 mM | 0.1211 mL | 0.6057 mL | 1.2115 mL | 3.0287 mL | |
| 50 mM | 0.0969 mL | 0.4846 mL | 0.9692 mL | 2.4230 mL | |
| 60 mM | 0.0808 mL | 0.4038 mL | 0.8077 mL | 2.0191 mL | |
| 80 mM | 0.0606 mL | 0.3029 mL | 0.6057 mL | 1.5143 mL | |
| 100 mM | 0.0485 mL | 0.2423 mL | 0.4846 mL | 1.2115 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
β-Caryophyllene-d2 Related Classifications
HY-N1415S Related Classifications
Powered by Bioz