1. Cell Cycle/DNA Damage
    Antibody-drug Conjugate/ADC Related
  2. DNA/RNA Synthesis
    ADC Cytotoxin
  3. γ-Amanitin

γ-Amanitin 

Cat. No.: HY-131081
Handling Instructions

γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin (HY-19610) and β-Amanitin (HY-125586).

For research use only. We do not sell to patients.

γ-Amanitin Chemical Structure

γ-Amanitin Chemical Structure

CAS No. : 21150-23-2

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Description

γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin (HY-19610) and β-Amanitin (HY-125586)[1].

IC50 & Target[1]

Traditional Cytotoxic Agents

 

Molecular Weight

902.97

Formula

C₃₉H₅₄N₁₀O₁₃S

CAS No.

21150-23-2

SMILES

O=[S](C[[email protected]](NC(CNC1=O)=O)C(N[[email protected]](C2=O)CC(N)=O)=O)C(N3)=C(C[[email protected]@H](C(NCC(N[[email protected]]1[[email protected]@H](C)CC)=O)=O)NC([[email protected]@H](NC([[email protected]](C4)N2C[[email protected]@H]4O)=O)[[email protected]@H](C)[[email protected]@H](O)C)=O)C(C3=C5)=CC=C5O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

γ-AmanitinDNA/RNA SynthesisADC CytotoxinmushroomADC cytotoxinRNA polymerase IImRNAprotein synthesisInhibitorinhibitorinhibit

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γ-Amanitin
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