4-Methylamphetamine hydrochloride
Based on 1 Customer Validation
4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces hypothermia in rats by binding to the 5-HT1A receptor. Additionally, 4-Methylamphetamine hydrochloride acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase the extracellular levels of these neurotransmitters. 4-Methylamphetamine hydrochloride can be used in the study of neurological disorders.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 41632-56-8
- Formula: C10H16ClN
- Molecular Weight:185.69
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
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5-HT1A Receptor |
Chemical Information
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CAS No. 41632-56-8
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Appearance Solid
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Molecular Weight 185.69
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Formula C10H16ClN
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Color White to off-white
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SMILES
NC(CC1=CC=C(C)C=C1)C.Cl
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Synonyms
4-MA hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 125 mg/mL (673.16 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Rubio M, et al. Serotonin is involved in the psychostimulant and hypothermic effect of 4-methylamphetamine in rats. Neurosci Lett. 2015 Mar 17;590:68-73. [Content Brief]
[2]. Blanckaert P, et al. 4-Methyl-amphetamine: a health threat for recreational amphetamine users. J Psychopharmacol. 2013 Sep;27(9):817-22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.3853 mL | 26.9266 mL | 53.8532 mL | 134.6330 mL |
| 5 mM | 1.0771 mL | 5.3853 mL | 10.7706 mL | 26.9266 mL | |
| 10 mM | 0.5385 mL | 2.6927 mL | 5.3853 mL | 13.4633 mL | |
| 15 mM | 0.3590 mL | 1.7951 mL | 3.5902 mL | 8.9755 mL | |
| 20 mM | 0.2693 mL | 1.3463 mL | 2.6927 mL | 6.7316 mL | |
| 25 mM | 0.2154 mL | 1.0771 mL | 2.1541 mL | 5.3853 mL | |
| 30 mM | 0.1795 mL | 0.8976 mL | 1.7951 mL | 4.4878 mL | |
| 40 mM | 0.1346 mL | 0.6732 mL | 1.3463 mL | 3.3658 mL | |
| 50 mM | 0.1077 mL | 0.5385 mL | 1.0771 mL | 2.6927 mL | |
| 60 mM | 0.0898 mL | 0.4488 mL | 0.8976 mL | 2.2439 mL | |
| 80 mM | 0.0673 mL | 0.3366 mL | 0.6732 mL | 1.6829 mL | |
| 100 mM | 0.0539 mL | 0.2693 mL | 0.5385 mL | 1.3463 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.