1. GPCR/G Protein
    Immunology/Inflammation
  2. CCR

NSC5844 (Synonyms: RE-640)

Cat. No.: HY-100033 Purity: >98.0%
Handling Instructions

NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.

For research use only. We do not sell to patients.

NSC5844 Chemical Structure

NSC5844 Chemical Structure

CAS No. : 140926-75-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 354 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties Target: CCR NSC5844 shows 3-fold increased activity in MDA-MB-468 cells (GI50 = 7.35 μM), compared to Chloroquine. NSC5844 shows lower activity (GI50 = 14.80 M) in the MCF-7 cell line. [1]

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.6091 mL 13.0456 mL 26.0913 mL
5 mM 0.5218 mL 2.6091 mL 5.2183 mL
10 mM 0.2609 mL 1.3046 mL 2.6091 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

383.27

Formula

C₂₀H₁₆Cl₂N₄

CAS No.

140926-75-6

SMILES

ClC1=CC=C2C(NCCNC3=CC=NC4=CC(Cl)=CC=C34)=CC=NC2=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
NSC5844
Cat. No.:
HY-100033
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