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  3. NSC5844

NSC5844 (Synonyms: RE-640)

Cat. No.: HY-100033 Purity: >98.0%
Handling Instructions

NSC5844 is a 4-aminoquinoline derivative, with antitumor and antimalarial activity.

For research use only. We do not sell to patients.

NSC5844 Chemical Structure

NSC5844 Chemical Structure

CAS No. : 140926-75-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 354 In-stock
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

NSC5844 is a 4-aminoquinoline derivative, with antitumor and antimalarial activity.

IC50 & Target

Parasite[2]

In Vitro

NSC5844 (Compound 10) is a 4-aminoquinoline derivative, and has antitumor activity with GI50s of 7.35 ± 0.10 μM and 14.80 ± 0.35 μM against MDA-MB-468 and MCF-7 cells, respectively[1]. NSC5844 (Compound 1) is cytotoxic to P. falciparum, inhibits the growth of chloroquine-sensitive (D-6) and -resistant (W-2) clones of P. falciparum, with IC50s of 17 and 27 nM, respectively[2].

Molecular Weight

383.27

Formula

C₂₀H₁₆Cl₂N₄

CAS No.

140926-75-6

SMILES

ClC1=CC=C2C(NCCNC3=CC=NC4=CC(Cl)=CC=C34)=CC=NC2=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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NSC5844
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