1. Immunology/Inflammation
    Metabolic Enzyme/Protease
  2. COX
    Lipoxygenase
  3. RWJ 63556

RWJ 63556 

Cat. No.: HY-U00022
Handling Instructions

RWJ 63556 is an orally active COX-2 selective/5-lipoxygenase inhibitor, with anti-inflammatory activities.

For research use only. We do not sell to patients.

RWJ 63556 Chemical Structure

RWJ 63556 Chemical Structure

CAS No. : 190967-35-2

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Description

RWJ 63556 is an orally active COX-2 selective/5-lipoxygenase inhibitor, with anti-inflammatory activities.

IC50 & Target[1]

COX-2

 

5-Lipoxygenase

 

In Vitro

RWJ 63556 is a potent inhibitor of leukocyte influx over a period of 24 hr and maintains its in vitro profile on eicosanoids[1].

In Vivo

RWJ 63556 (1 mg/kg, i.v.) significantly inhibits the development of SP-induced oedema[2].

Molecular Weight

287.33

Formula

C₁₁H₁₀FNO₃S₂

CAS No.

190967-35-2

SMILES

CS(=O)(NC1=CC=C(OC2=CC=C(F)C=C2)S1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

RWJ 63556RWJ63556RWJ-63556COXLipoxygenaseCyclooxygenaseLOXInhibitorinhibitorinhibit

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RWJ 63556
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