Adrenergic Receptor Agonist
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Prenalterol hydrochloride
0 ImagesCat. No.: HY-112071ACAS No.: 61260-05-7Prenalterol hydrochloride is a partial adrenal agonist with functional β1-receptor specificity and positive inotropic effects. Prenalterol hydrochloride is effective in suppressing acute heart failure, low output syndrome after myocardial infarction, shock, and reducing orthostatic hypotension in Shy-Drager syndrome.
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Ractopamine
0 ImagesCat. No.: HY-113781CAS No.: 97825-25-7Synonyms: LY031537 free baseRactopamine (LY031537 free base) is a potent and orally active β-adrenergic receptor (βAR) agonist with Kd value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC50 of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs.
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BMS-210285
0 ImagesCat. No.: HY-117084CAS No.: 344607-69-8BMS-210285 is a highly selective agonist for the 3 receptor. BMS-210285 has a Ki of 9 nM at the human 3-adrenoceptor. BMS-210285 possesses a 3 intrinsic activity of 83% relative to isoproterenol. BMS-210285 can be studied for obesity and type 2 diabetes research.
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BRL-37344
0 ImagesCat. No.: HY-101325BCAS No.: 114333-71-0BRL-37344 is a β-adrenoceptor agonist with EC50 values of 5.3, 18 and 570 nM for β3, β2 and β1. BRL-37344 induces concentration-dependent increases in atria1 rate, relaxation of guinea pig trachea and lipolysis of brown adipocytes.
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Flerobuterol hydrochloride
0 ImagesCat. No.: HY-106361ACAS No.: 82101-08-4Synonyms: CRL 40827 hydrochlorideFlerobuterol hydrochloride is a beta-adrenoceptor agonist with antidepressant activity. Flerobuterol hydrochloride enhances serotonergic neurotransmission.
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β2AR agonist /M-receptor antagonist-1
0 ImagesCat. No.: HY-148533CAS No.: 2772700-36-2β2AR agonist /M-receptor antagonist-1 is a potent dual muscarinic antagonist/beta 2 agonist (MABA). β2AR agonist /M-receptor antagonist-1 potently relaxes either Carbachol?(HY-B1208)-induced contraction, in the absence (MABA) or presence of Propranolol?(HY-B1208), or Histamine(HY-B1204)-induced contraction (β2).
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Brombuterol-d9 hydrochloride
0 ImagesCat. No.: HY-131104ASCAS No.: 1353867-94-3Synonyms: Bromobuterol D9 hydrochlorideBrombuterol-d9 (hydrochloride) is a deuterium labeled Brombuterol hydrochloride. Brombuterol hydrochloride is a β-adrenergic receptor agonist.
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UK 14819
0 ImagesCat. No.: HY-123285CAS No.: 91147-46-5Synonyms: 5-Desbromo, 5-chloro brimonidineUK 14819 (5-Desbromo, 5-chloro brimonidine) is an α2-adrenoceptor agonist. UK 14819 inhibits stimulation-induced contractions of rabbit distal colon with an IC50 of 6.66 nM.
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Phenylethanolamine A
0 ImagesCat. No.: HY-131103CAS No.: 1346746-81-3Phenylethanolamine A acts as a β-adrenergic agonist. Phenylethanolamine A is a byproduct during the Ractopamine synthesis process.
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α1A Adrenoceptor agonist-1
0 ImagesCat. No.: HY-W1058741CAS No.: 945389-41-3α1A Adrenoceptor agonist-1 (compound 13) is an α1A adrenoceptor (α1A adrenoceptor) agonist with an EC50 of 385 nM for α1A. α1A Adrenoceptor agonist-1 exhibits in vitro functional agonistic activity targeting adrenoceptors. α1A Adrenoceptor agonist-1 can be used for the research of stress urinary incontinence.
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CHF-6550
0 ImagesCat. No.: HY-163702CAS No.: 3052116-62-5CHF-6550 is an antagonist for muscarinic M3 receptor and an agonist for β2 adrenoceptor (MABA), with pKi of 9.3 and 10.6, respectively. CHF-6550 exhibits good hepatocyte clearance in rat models and good pharmacokinetic characteristics in guinea pigs.
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Tasipimidine
0 ImagesCat. No.: HY-109075CAS No.: 1465908-70-6Tasipimidine is an orally active and selective α2A-adrenoceptor agonist with a pEC50 of 7.57 for human α2A-adrenoceptors and an EC50 of 5.7 nM for rat α2-adrenoceptor. Tasipimidine can be utilized in research related to situational anxiety and fear.
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Vilanterol acetate
0 ImagesCat. No.: HY-14300DCAS No.: 503068-35-7Synonyms: GW642444 acetateVilanterol (GW642444) acetate is a long-acting β2 adrenergic receptor agonist. Vilanterol acetate has pEC50 values for β2-AR, β1-AR, and β3-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol acetate selectively activates airway β2 adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol acetate can be used in asthma research[1][2].
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KUC-7322
0 ImagesCat. No.: HY-116169CAS No.: 255734-04-4KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
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Povafonidine
0 ImagesCat. No.: HY-147299CAS No.: 177843-85-5Synonyms: PGE-6201204Povafonidine (PGE-6201204) is a potent α2 adrenoreceptor agonist. Povafonidine can constrict blood vessels and reduce mucosal congestion. Povafonidine can be used for nasal congestion research.
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BMS-196085
0 ImagesCat. No.: HY-120223CAS No.: 170686-10-9BMS-196085 is an orally active, potent and selective full agonist against human β3 adrenergic receptor with a Ki value of 21 nM. BMS-196085 also has partial agonist activity at the β1 receptor. BMS-196085 is promising for research of obesity and type-II diabetes.
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Chloroguanabenz acetate
0 ImagesCat. No.: HY-175136CAS No.: 2242615-97-8Synonyms: GAh acetateChloroguanabenz (acetate) is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz. Chloroguanabenz (acetate) can inhibit the formation of prion in yeast and mammalian in vitro assays. Chloroguanabenz (acetate) can reduce the levels of truncated Huntingtin derivative Htt48 in HEK293T cells. Chloroguanabenz (acetate) can be studied in research on Huntington’s disease.
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Zilpaterol-d7
0 ImagesCat. No.: HY-A0072SCAS No.: 1217818-36-4Zilpaterol-d7 is a deuterium Zilpaterol. Zilpaterol is a β-adrenergic agonist that have been widely used to feed cattle.
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Navafenterol saccharinate
0 ImagesCat. No.: HY-120802ACAS No.: 1648550-37-1Synonyms: AZD-8871 saccharinate; LAS191351 saccharinateNavafenterol (AZD-8871) saccharinate is an inhaled dual-acting, potent, selective, and long-lasting M3-antagonist/β2-agonist (MABA) with long-lasting effects and favorable safety profile. The pIC50 is 9.5 for human M3 receptor, and the pEC50 is 9.5 for β2-adrenoceptor. Navafenterol saccharinate can be used for the research of chronic obstructive pulmonary disease (COPD). Bronchoprotective and antisialagogue effects. Favorable cardiovascular profile.
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β2AR agonist 3
0 ImagesCat. No.: HY-149728CAS No.: 2304455-74-9β2AR agonist 3 (compound 9a) is a β2-adrenergic receptor (β2AR) agonist. β2AR agonist 3 can be used for type 2 diabetes research.
