1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N10230
    MC 304
    MC 304 is a β-resorcylate isolated from cultures of Phanerochaete chrysosporium. MC 304 has antibacterial activity. MC 304 shows a stimulatory effect on root elongation of Lepidium satiuum.
    MC 304
  • HY-122467
    Kumbicin C
    Kumbicin C is a bis-indolyl benzenoid compound from an Australian soil fungus, Aspergillus kumbius. Kumbicin C inhibits the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis.
    Kumbicin C
  • HY-P5657
    Maximin H5
    Maximin H5 is an antimicrobial peptide derived from toad Bombina maxima.
    Maximin H5
  • HY-106946
    E 5065
    Inhibitor
    E 5065 is an orally active antibacterial agent. E 5065 exhibits potent in vitro activity against Gram-negative microorganisms, Gram-positive cocci, and anaerobes. E 5065 exhibits an MIC90 of 0.5 μg/mL against Clostridium spp. E 5065 provides protection against experimental infections caused by P. aeruginosa.
    E 5065
  • HY-P5548
    CaLL
    Inhibitor
    CaLL is an antimicrobial peptide. CaLL has antibacterial activity against B. anthracis, B. anthracis (vegetative), and B. cepacia (MIC: 7.8, 31.3, 31.3 μg/mL).
    CaLL
  • HY-W005327R
    1-Hydroxy-2-butanone (Standard)
    Inhibitor
    1-Hydroxy-2-butanone (Standard) is the analytical standard of 1-Hydroxy-2-butanone. This product is intended for research and analytical applications. 1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects[1][2].
    1-Hydroxy-2-butanone (Standard)
  • HY-N17582
    (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside
    Inhibitor
    (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside is a Streptococcus mutans Sortase A inhibitor with an IC50 of 37.3 μM. (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside inhibits transpeptidase activity linked to Gram-positive bacterial surface protein anchoring. (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside can be used for the research of dental caries.
    (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside
  • HY-N13917
    Argyrin B
    Inhibitor
    Argyrin B, a natural product cyclic peptide, is a reversible, non-competitive immunoproteasome inhibitor. Argyrin B shows selective inhibition of the β5i and β1i sites of the immunoproteasome over the β5c and β1c sites of the constitutive proteasome with nearly 20-fold selective inhibition of β1i over the homologous β1c. Argyrin B has antibacterial effects.
    Argyrin B
  • HY-143236
    DHFR-IN-1
    Inhibitor
    DHFR-IN-1 (compound 12) is a potent and selective DHFR (dihydrofolate reductase)inhibitor, with an IC50 of 40.71 nM. DHFR-IN-1 exhibits promising antibacterial activity against gram-positive and gram-negative bacteria. DHFR-IN-1 exhibits moderate antifungal activities. DHFR-IN-1 exhibits a high synergistic effect with Levofloxacin (HY-B0330), where the FIC (fractional inhibitory concentration index) value is 0.249.
    DHFR-IN-1
  • HY-182058
    ATM potentiator-1
    Inhibitor
    ATM potentiators-1 is a quercetin derivative that synergistically enhances the antibacterial activity of Aztreonam (ATM, HY-B0129) against metallo-β-lactamase-producing Pseudomonas aeruginosa. ATM potentiators-1 inhibits NDM-1, OXA-10, VIM-2, KPC-2, and OXA-48, suppressing the efflux pump activity of Pseudomonas aeruginosa. When used in combination with CCCP (HY-100941), it exhibits a synergistic inhibitory effect. ATM potentiators-1 is applicable to research related to Pseudomonas aeruginosa infections.
    ATM potentiator-1
  • HY-N18755
    Solanum xanthocarpum extract
    Solanum xanthocarpum extract possesses anti-inflammatory, analgesic, antibacterial, and antiviral properties, and is rich in various bioactive compounds, such as alkaloids, triterpenoids, saponins, steroidal glycoalkaloids, and flavonoids.
    Solanum xanthocarpum extract
  • HY-178949
    MRSA antibiotic 3
    Inhibitor
    MRSA antibiotic 3 (Compound C8) is a small-molecule antibiotic active against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA), showing a MIC of 0.5 μg/mL against the standard S. aureus strain (ATCC 29213). MRSA antibiotic 3 potently inhibits the ATPase activity of S. aureus DNA gyrase with an IC50 of 0.32 μM. MRSA antibiotic 3 exhibits strong inhibitory activity against five clinical MRSA isolates, with MIC values ranging from 0.5 to 1 μg/mL. MRSA antibiotic 3 demonstrates negligible cytotoxicity at effective antibacterial concentrations and causes no hemolysis in erythrocytes even at extremely high concentrations. MRSA antibiotic 3 shows significant protective effects in both Galleria mellonella infection and murine sepsis models.
    MRSA antibiotic 3
  • HY-B1747A
    Pyrithione sodium
    Inhibitor
    Pyrithione sodium has poor skin penetration.
    Pyrithione sodium
  • HY-W099580S
    Hexadecane-1,2-13C2
    Hexadecane-1,2-13C2 (n-Hexadecane-1,2-13C2) is the 13C labeled Hexadecane (HY-W099580). Hexadecane (n-Hexadecane) is a saturated hydrocarbon of alkanes or paraffins and can be used as an organic solvent. Hexadecane is a component of petroleum, belongs to hydrophobic substrates, and is a model substance for studying bacterial degradation of hydrophobic compounds.
    Hexadecane-1,2-<sup>13</sup>C<sub>2</sub>
  • HY-P11138
    Lactocin 705α
    Lactocin 705α (Lac705α) is a peptide component of Lactocin 705. Lactocin 705α can interact with zwitterionic DPPC bilayers. Lactocin 705α can induce the dehydration of the bilayer interfacial region. Lactocin 705α can be used in the research of bacterial infections.
    Lactocin 705α
  • HY-N17566
    Eukovoside
    Inhibitor
    Eukovoside is a cinnamic acid derivative found in Euphrasia regelii with anti-inflammatory, antioxidant, antibacterial, antiallergic, and antihistamine activity. Eukovoside can be used for the research of hyperglycemic diseases, eye inflammation, upper respiratory passages inflammation, hay fever, conjunctivitis, colds, influenza, sinusitis.
    Eukovoside
  • HY-N16400
    Aspergillumarin A
    Inhibitor
    Aspergillumarin A is a dihydroisocoumarin derivative with various biological activity. Aspergillumarin A inhibits cell proliferation by inducing G0/G1 phase arrest in HepG2 hepatocellular carcinoma cells.. Aspergillumarin A exhibits weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis. Aspergillumarin A can be used for the study of hepatocellular carcinoma (HCC)
    Aspergillumarin A
  • HY-142695
    Antibacterial synergist 1
    Antibacterial synergist 1 (compound 20P) is a bacterial biofilm inhibitor. Antibacterial synergist 1 inhibits the production of pyocyanin and biofilm formation with IC50s of 8.6 and 4.5 μM, respectively. Antibacterial synergist 1 has the potential for the research of P. aeruginosa infections.
    Antibacterial synergist 1
  • HY-N12461
    Cucurbitacin F
    Inhibitor
    Cucurbitacin F is a tetracyclic protostane-type triterpenoid with low toxicity, antibacterial and anti-inflammatory activities, and is also a related compound of Cucurbitacin B (HY-N0416). Cucurbitacin F widely exists in plants such as Cucurbitaceae plants, Quisqualis indica and Sorbaria sorbifolia. Cucurbitacin F acts as an actin aggregator and reduces cell viability in a dose-dependent manner. Cucurbitacin F induces apoptosis by triggering G2/M phase cell cycle arrest and activating the caspase-3-dependent apoptosis.
    Cucurbitacin F
  • HY-119901
    Eupatarone
    Inhibitor
    Eupatarone (Caleprunin B) is a bacterial inhibitor. Eupatarone can be obtained from Calea platylepis.
    Eupatarone
Cat. No. Product Name / Synonyms Application Reactivity