CMV
Cytomegalovirus
Cytomegalovirus (CMV) is a double-stranded DNA virus and is a member of the ubiquitous family of herpesviruses. Cytomegaloviruses escape immunological clearance and persist throughout life in the infected host. Yet, the stability of the balance of this virus-host interaction is dependent upon the state of the cellular immune response, and usually requires the function of specific CD8 T lymphocytes.
Human cytomegalovirus is a member of the viral family known as herpesviruses, Herpesviridae, or human herpesvirus-5 (HHV-5). Human cytomegalovirus infections commonly are associated with the salivary glands. CMV infection may be asymptomatic in healthy people, but it can be life-threatening in an immunocompromised patient. Congenital cytomegalovirus infection can cause morbidity and even death. After infection, CMV often remains latent, but it can reactivate at any time. Eventually, it causes mucoepidermoid carcinoma, and it may be responsible for prostate cancer.
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CMV Related Products (107)
Related Products (107)
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Ancitabine hydrochloride (Standard)
0 ImagesSynonyms: Cyclocytidine hydrochloride (Standard); Cyclo-CMP hydrochloride (Standard); Cyclo-C (Standard)Ancitabine hydrochloride (Standard) is the analytical standard of Ancitabine hydrochloride. This product is intended for research and analytical applications. Ancitabine (Cyclocytidine) hydrochloride is a cytarabine derivative that inhibits viral replication. Ancitabine hydrochloride blocks vaccinia virus DNA replication, the progression of viral protein synthesis from early to late stages, and one-step growth of vaccinia virus. Ancitabine hydrochloride is applicable to research related to vaccinia virus infection, leukemia, human cytomegalovirus infection and colorectal cancer.
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Tricin-d6
0 ImagesCat. No.: HY-N1127SCAS No.: 1178549-27-3Tricin-d6 is the deuterium labeled Tricin. Tricin is a natural flavonoid present in large amounts in Triticum aestivum. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7.
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Cyclic HPMPC
0 ImagesCat. No.: HY-147014CAS No.: 127757-45-3Cyclic HPMPC is a potent antiviral agent. Cyclic HPMPC can increase arterial oxygen saturation levels in lethal vaccinia virus (IHD strain)-infected mice. Cyclic HPMPC improves the outcome of congenital guinea pig cytomegalovirus (GPCMV) infection and decreases viral replication in guinea pig model.
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Ancitabine
0 ImagesCat. No.: HY-N0093ACAS No.: 31698-14-3Synonyms: Cyclocytidine; Cyclo-CMPAncitabine (Cyclocytidine) is a cytarabine derivative that inhibits viral replication. Ancitabine blocks vaccinia virus DNA replication, the progression of viral protein synthesis from early to late stages, and one-step growth of vaccinia virus. Ancitabine is applicable to research related to vaccinia virus infection, leukemia, human cytomegalovirus infection and colorectal cancer.
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Valganciclovir-d8
0 ImagesCat. No.: HY-A0032ASCAS No.: 1132088-63-1Valganciclovir-d8 is the deuterium labeled Valganciclovir . Valganciclovir , the L-valyl ester of ganciclovir, is actually a proagent for ganciclovir.
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VTEHDTLLY
0 ImagesCat. No.: HY-P11179CAS No.: 481651-50-7VTEHDTLLY is a HLA class I-restricted CMV peptide epitope. VTEHDTLLY can be used in the research of CMV-specific T cell expansion.
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CEF20
0 ImagesCat. No.: HY-P1780CAS No.: 153045-21-7CEF20 is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
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BDCRB
0 ImagesCat. No.: HY-19296CAS No.: 142356-43-2Synonyms: 2-Bromo-5,6-dichloro-1-β-D-ribofuranosyl benzimidazoleBDCRB is a selective Human cytomegalovirus (HCMV) inhibitor through blocking the maturational cleavage of high-molecular-weight DNA. BDCRB shows a mean IC50 of 0.03 μM for viral yield at 72 h postinfection.
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Ganciclovir sodium (Standard)
0 ImagesSynonyms: BW 759 sodium (Standard); 2'-Nor-2'-deoxyguanosine sodium (Standard)Ganciclovir (sodium) (Standard) is the analytical standard of Ganciclovir (sodium). This product is intended for research and analytical applications. Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain[1][2][3].
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Tricin (Standard)
0 ImagesTricin (Standard) is the analytical standard of Tricin. This product is intended for research and analytical applications. Tricin is a natural flavonoid found in large amounts in wheat. Tricin inhibits HCMV replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells by upregulating the expression of FAK-targeting microRNA-7 .
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Maribavir-d7
0 ImagesCat. No.: HY-16305S2Synonyms: 1263W94-d7; BW1263W94-d7; GW257406X-d7
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IE1 peptide
0 ImagesCat. No.: HY-P10509CAS No.: 127902-44-7IE1 peptide refers to an antigenic peptide encoded by the immediate early (IE) gene of mouse cytomegalovirus (mCMV). IE1 peptide is one of the key antigenic peptides expressed during mCMV infection, plays a role in transcriptional activation in the life cycle of mCMV, and is one of the earliest genes expressed in the viral replication cycle. IE1 peptide is an important target for CD8+ T cell response and can be used to study the host immune response to mCMV infection.
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Floxuridine-13C,15N2
0 ImagesCat. No.: HY-W766548Synonyms: 5-Fluorouracil 2'-deoxyriboside-13C,15N2Floxuridine-13C,15N2 (5-Fluorouracil 2'-deoxyriboside-13C,15N2) is the 13C- and 15N-labeled labeled Floxuridine (HY-B0097). Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis. Floxuridine has antiviral effects against HSV and CMV.
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Fomivirsen sodium scrambled negative control
0 ImagesCat. No.: HY-109528AFomivirsen sodium scrambled negative control is the sequence scrambled negative control of Fomivirsen sodium.
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Letermovir (GMP)
0 ImagesCat. No.: HY-15233GCAS No.: 917389-32-3Synonyms: AIC246 (GMP); MK-8228 (GMP)Letermovir (GMP) is the GMP grade of Letermovir (HY-15233). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Letermovir (GMP) is an orally active CMV inhibitor. Letermovir (GMP) targets the CMV terminase complex rather than CMV DNA polymerase and exerts its antiviral activity. Letermovir (GMP) can be used in the study of CMV infection.
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SB-734117
0 ImagesCat. No.: HY-114005CAS No.: 607368-97-8SB-734117 is a human cytomegalovirus (HCMV) replication inhibitor that prevents CREB and histone H3 post-translational modifications.
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BAY-43-9695
0 ImagesBAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC50 of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC50 of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261).
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T-22
0 ImagesCat. No.: HY-P10685CAS No.: 147658-54-6Synonyms: [Tyr5,12,Lys7]-Polyphemusin II
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Antiviral agent 37
0 ImagesCat. No.: HY-155795CAS No.: 357163-03-2
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Valganciclovir-d5 TFA
0 ImagesCat. No.: HY-A0032SCAS No.: 1402924-31-5Valganciclovir-d5 (TFA) is the deuterium labeled Valganciclovir TFA. Valganciclovir, the L-valyl ester of ganciclovir, is actually a proagent for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.
