2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17182
    Cyclocarioside I
    Cyclocarioside I is a natural triterpene.
    Cyclocarioside I
  • HY-N16957
    3α,30-Diacetoxy-12α-hydroxy-23-oxoeupha-7,24-dien-21,16β-olid-28-oic acid 28-O-β-D-glucopyranosyl ester
    3α,30-Diacetoxy-12α-hydroxy-23-oxoeupha-7,24-dien-21,16β-olid-28-oic acid 28-O-β-D-glucopyranosyl ester is a natural triterpene.
    3α,30-Diacetoxy-12α-hydroxy-23-oxoeupha-7,24-dien-21,16β-olid-28-oic acid 28-O-β-D-glucopyranosyl ester
  • HY-111761
    DIQ3
    DIQ3 is a potent anti-cancer agent, nontoxic to normal human cell lines.
    DIQ3
  • HY-W385577A
    (S)-2-Benzylpyrrolidine hydrochloride
    (S)-2-Benzylpyrrolidine hydrochloride (Compound s1) serves as a METH hapten scaffold. (S)-2-Benzylpyrrolidine hydrochloride attenuates Methamphetamine-induced hyperlocomotion, hyperthermia and respiratory depression. (S)-2-Benzylpyrrolidine hydrochloride alleviates Fentanyl-induced respiratory depression.
    (S)-2-Benzylpyrrolidine hydrochloride
  • HY-120768
    A-30312
    A-30312 is a compound that can overcome multidrug resistance and has the activity of reversing multidrug resistance. A-30312 can enhance the cytotoxicity of antitumor compounds in multidrug-resistant cells, increase the accumulation of compounds in cells, inhibit the efflux of compounds, and compared with calcium antagonists, it has no serious hypotensive effect. Its activity may be unrelated to the ability to block calcium transport.
    A-30312
  • HY-N3843
    Ergosta-5,24(28)-diene-3β,7α,16β-triol
    Ergosta-5,24(28)-diene-3β,7α,16β-triol is a natural steroid.
    Ergosta-5,24(28)-diene-3β,7α,16β-triol
  • HY-N17304
    10S,13aR-Antofine N-oxide
    10S,13aR-Antofine N-oxide is a phenanthroindolizidine N-oxide alkaloid and cytotoxic agent found in Cynanchum vincetoxicum. 10S,13aR-Antofine N-oxide exerts cytotoxic effects in drug-sensitive (KB-3-1, IC50 = 0.11 μM) and multi-drug-resistant (KB-V1, IC50 = 0.16 μM) carcinoma cells. 10S, 13aR-Antofine N-oxide acts as a poor substrate for the P-glycoprotein (P-170) efflux pump. 10S,13aR-Antofine N-oxide can be used for the research of cancers.
    10S,13aR-Antofine N-oxide
  • HY-N18129
    Stigmastane
    Stigmastane is a natural product that can be found in soybeans.
    Stigmastane
  • HY-N13758
    Thalmineline
    Thalmineline is a natural alkaloid.
    Thalmineline
  • HY-N16862
    4-Gingerol
    4-Gingerol is a natural phenolic compound.
    4-Gingerol
  • HY-148766
    VU661
    VU661, a phenazine carboxamide, is a modulator of circadian rhythms to produce a period lengthening of the circadian rhythm. VU661 is a redox-active small molecule .
    VU661
  • HY-N17571
    Salicortinol
    Salicortinol is a salicin derivative. Salicortinol is present in the leaves of Populus euphratica Oliv.
    Salicortinol
  • HY-N18017
    Shinjuglycoside C
    Shinjuglycoside C (Compound 3) is a quassinoid glycoside that can be isolated from the seeds of Ailanthus altissima. Shinjuglycoside C exhibits a bitter taste.
    Shinjuglycoside C
  • HY-N11731
    Rotenonone
    Rotenonone is a derivative of Rotenone (HY-B1756), with a LD50 of 0.68 μg/g against larvae of Spodoptera litura.
    Rotenonone
  • HY-N16473
    14,15-Epoxyazadiradione
    14,15-Epoxyazadiradione is a triterpenoid found in Azadirachta indica. Azadirachta indica shows anti-infection, anti-inflammatory and anticancer activities. Azadirachtin H can be used for the researches of cancer, infection and inflammation.
    14,15-Epoxyazadiradione
  • HY-N17231
    Erythrinin E
    Erythrinin E is a natural flavonoid.
    Erythrinin E
  • HY-116137
    Nav1.7-IN-17
    Nav1.7-IN-17 is an active compound.
    Nav1.7-IN-17
  • HY-N15715
    Acoraminol B
    Acoraminol B is one of the stereoisomers of phenylpropanoids, the other of which is Acoraminol A (HY-N15714), which can be isolated from the methanol extract of the rhizome of Acorus tatarinowii. Acoraminol B has weak cytotoxic effects on several human tumor cell lines (IC50>30 μM).
    Acoraminol B
  • HY-B1022A
    Dimesna free acid
    Dimesna (BNP-7787) free acid, the disulfide form of Mesna (HY-13679), is a platinum-related toxicity protective agent. Dimesna free acid converts to Mesna, which in turn inactivates toxic platinum substances. Dimesna free acid does not interfere with the antitumor activity of platinum compounds. Dimesna free acid does not affect the antiproliferative effects of Cisplatin (HY-17394) or Carboplatin (HY-17393). Dimesna free acid counteracts Cisplatin-induced nephrotoxicity. Dimesna free acid exerts selective protective effects on the kidneys. Dimesna free acid can be used in studies related to ovarian cancer and Cisplatin-induced nephrotoxicity.
    Dimesna free acid
  • HY-N17511
    Allivictoside C
    Allivictoside C is a natural product that can be found in ginkgo.
    Allivictoside C