Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11126)
Related Products (11126)
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Homovanillic acid-d2
0 ImagesSynonyms: Vanilacetic acid-d2Homovanillic acid-d2 (Vanilacetic acid-d2) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
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1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4
0 ImagesCat. No.: HY-115702SCAS No.: 211106-54-6Synonyms: (Rac)-PAF (C16)-d41-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4 ((Rac)-PAF (C16)-d4) is the deuterium labeled 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine is an endogenous inflammatory lipid mediator. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine acts as a high-affinity agonist for PAFR (GPCR), inducing platelet aggregation, vascular permeability, and leukocyte chemotaxis at extremely low concentrations. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine exerts its effects via cell surface receptors to regulate inflammation.
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Riociguat-13C,d6
0 ImagesCat. No.: HY-14779SPurity: 99.0%Synonyms: BAY 632521-13C,d6Riociguat-13C,d6 is the 13C and deuterium labeled Riociguat (HY-14779). Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.
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Norethindrone Acetate-2,2,4,6,6,10-d6
0 ImagesCat. No.: HY-W748961Norethindrone Acetate-2,2,4,6,6,10-d6 is deuterated labeled Norethindrone Acetate-2,2,4,6,6,10.
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Flupyradifurone-d5
0 ImagesCat. No.: HY-W750777CAS No.: 2732873-32-2Flupyradifurone-d5 is the deuterium labeled Flupyradifurone (HY-145295). Flupyradifurone is a systemic?nAChR?agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide?insecticide.
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Ethyl palmitate-d31
0 ImagesSynonyms: Ethyl hexadecanoate-d31Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent.
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Citrinin-13C13
0 ImagesCat. No.: HY-N6746S1Purity: 98%Synonyms: NSC 186-13C13Citrinin-13C13 (NSC 186-13C13) is the 13C labeled Citrinin (HY-N6746). Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity.
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Disulfiram-d20
0 ImagesCat. No.: HY-W127834CAS No.: 1216403-88-1Disulfiram-d20 is deuterium labeled Disulfiram-d20.
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Salicylic acid-13C6
0 ImagesCat. No.: HY-B0167S1CAS No.: 1189678-81-6Synonyms: 2-Hydroxybenzoic acid-13C6Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity.
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Acetophenone-d8
0 ImagesSynonyms: 1-Phenylethan-1-One-d8Acetophenone-d8 is the deuterium labeled Acetophenone. Acetophenone is an organic compound with simple structure.
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N-Formylglycine-d2
0 ImagesCat. No.: HY-128735SN-Formylglycine-d2 is the deuterated labeled N-Formylglycine (HY-128735). N-Formylglycine is an endogenous metabolite.
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2-Methylcitric acid-d3 trisodium
0 ImagesCat. No.: HY-113371ASCAS No.: 2483831-23-6Synonyms: Methylcitric acid-d3 trisodium2-Methylcitric acid-d3 (Methylcitric acid-d3) trisodium is deuterium-labeled 2-Methylcitric acid (trisodium) (HY-113371A).
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1,5-Anhydrosorbitol-13C
0 Images1,5-Anhydrosorbitol-13C is the 13C labeled 1,5-Anhydrosorbitol. 1,5-Anhydrosorbitol is a short-term marker for glycemic cont.
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Boc-Glycine-d2
0 ImagesSynonyms: N-tert-Butoxycarbonyl-2-aminoacetic acid-d2; NSC 127669-d2Boc-Glycine-d2 is the deuterium labeled Boc-Glycine.
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Daidzein-d6
0 ImagesCat. No.: HY-N0019S1CAS No.: 291759-05-2
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Rabeprazole-d4
0 ImagesCat. No.: HY-B0656SCAS No.: 934295-48-4Synonyms: LY307640-d4Rabeprazole-d4 is a deuterium labeled Rabeprazole. Rabeprazole is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux.
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Nicotinamide-15N,13C3
0 ImagesCat. No.: HY-B0150S1CAS No.: 2117346-85-5Synonyms: Niacinamide-15N,13C3; Nicotinic acid amide-15N,13C3Nicotinamide-15N,13C3 is the 13C-labeled and 15N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
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Spironolactone-d6-1
0 ImagesCat. No.: HY-B0561S4Purity: 99.26%Spironolactone-d6-1 is the deuterium labeled Spironolactone (HY-B0561). Spironolactone is an aldosterone antagonist that acts on the aldosterone mineralocorticoid receptor (IC50=24 nM) and androgen receptor (IC50=77 nM), promotes podocyte autophagy and regulates pain. Spironolactone improves hypertension-related vascular hypertrophy and remodeling by reducing angiotensin II (Ang II)-induced inflammation, reduces aldosterone-induced vascular and soft tissue calcification through PIT1-dependent signaling, and alleviates vascular dysfunction in type II diabetic mice by reducing oxidative stress and restoring NO/GC signaling; at low concentrations, it and its metabolites can interfere with aldosterone biosynthesis in the adrenal cortex and inhibit voltage-dependent Ca2+ channels to exert antihypertensive effects.
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4-Formylaminoantipyrine-d3
0 ImagesCat. No.: HY-133588S4-Formylaminoantipyrine-d3 is the deuterium labeled 4-Formylaminoantipyrine (HY-133588). 4-Formylaminoantipyrine is an excreted metabolite of Aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo.
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Rosuvastatin-d6 calcium
0 ImagesCat. No.: HY-17504SRosuvastatin-d6 calcium is the deuterated-labeled Rosuvastatin Calcium (HY-17504). Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
