Zaurategrast ethyl ester sulfate
Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester proagent of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1214261-78-5
- Fòrmula: C28H29BrN4O3.1/2H2O4S
- Peso molecular:647.54
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Other In-stock Forms of Zaurategrast ethyl ester sulfate
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-13535
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TR-14035α4β7/α4β1 Antagonist -
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FirategrastIntegrin Antagonist -
HY-17369
Tirofiban hydrochloride monohydrateGp IIb/IIIa Receptor Antagonist -
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ZaurategrastIntegrin Inhibitor -
HY-75385
Zaurategrast ethyl ester
Actividad biológica
Descripciòn
IC50 & Target
α4β1/α4β7 integrin[1]
In Vitro
Zaurategrast ethyl ester sulfate (CDP323 sulfate), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1214261-78-5
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Peso molecular 647.54
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Fòrmula C28H29BrN4O3.1/2H2O4S
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SMILES
O=C(OCC)[C@H](CC1=CC=C(NC2=NC=CC3=C2C=NC=C3)C=C1)NC4=C(Br)C(C45CCCCC5)=O.O=S(O)(O)=O
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Synonyms
CDP323 sulfate; UCB1184197 sulfate
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91. [Content Brief]
[2]. Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases? Drug Discov Today. 2007 Jul;12(13-14):569-76. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zaurategrast ethyl ester sulfate Related Classifications
HY-75385A Related Classifications
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