1. Cytoskeleton
  2. Integrin

Zaurategrast ethyl ester (Synonyms: CDP323; UCB1184197)

Cat. No.: HY-75385
Handling Instructions

Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders.

For research use only. We do not sell to patients.

Zaurategrast ethyl ester Chemical Structure

Zaurategrast ethyl ester Chemical Structure

CAS No. : 455264-30-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 247 In-stock
Estimated Time of Arrival: December 31
5 mg USD 204 In-stock
Estimated Time of Arrival: December 31
10 mg USD 360 In-stock
Estimated Time of Arrival: December 31
25 mg USD 708 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Other Forms of Zaurategrast ethyl ester:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2].

IC50 & Target

α4β1/α4β7 integrin[1]

In Vitro

Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8200 mL 9.0998 mL 18.1997 mL
5 mM 0.3640 mL 1.8200 mL 3.6399 mL
10 mM 0.1820 mL 0.9100 mL 1.8200 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

549.46

Formula

C₂₈H₂₉BrN₄O₃

CAS No.

455264-30-9

SMILES

O=C(OCC)[[email protected]](CC1=CC=C(NC2=NC=CC3=C2C=NC=C3)C=C1)NC4=C(Br)C(C45CCCCC5)=O

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Zaurategrast ethyl ester
Cat. No.:
HY-75385
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Zaurategrast ethyl ester

Cat. No.: HY-75385