1. Cell Cycle/DNA Damage
    Epigenetics
  2. PARP
  3. Amelparib

Amelparib (Synonyms: JPI-289)

Cat. No.: HY-116218
Handling Instructions

Amelparib is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib inhibits PARP-1 activity (IC50 =18.5 nmol/L) and cellular PAR formation (IC50 =10.7 nmol/L) in the nanomolar range. Amelparib is a potential neuroprotective agent. Amelparib has the potential for the research of acute ischaemic stroke.

For research use only. We do not sell to patients.

Amelparib Chemical Structure

Amelparib Chemical Structure

CAS No. : 1227156-72-0

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Description

Amelparib is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib inhibits PARP-1 activity (IC50 =18.5 nmol/L) and cellular PAR formation (IC50 =10.7 nmol/L) in the nanomolar range. Amelparib is a potential neuroprotective agent. Amelparib has the potential for the research of acute ischaemic stroke[1].

Molecular Weight

343.42

Formula

C19H25N3O3

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Amelparib
Cat. No.:
HY-116218
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