2. Cell Cycle/DNA Damage Epigenetics Immunology/Inflammation Apoptosis
  3. HDAC DNA/RNA Synthesis NO Synthase Apoptosis
  4. anti-TNBC agent-12

anti-TNBC agent-12 (Compound 23a) is a multi-target antitumor agent targeting HDAC6 (IC50=30.3 nM), DNA, and inducing nitric oxide (NO) release. anti-TNBC agent-12 induces tumor cell apoptosis and G2/M phase cell cycle arrest. anti-TNBC agent-12 is promising for research of triple-negative breast cancer (TNBC).

For research use only. We do not sell to patients.

anti-TNBC agent-12

anti-TNBC agent-12 Chemical Structure

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anti-TNBC agent-12 Related Antibodies

Top Publications Citing Use of Products

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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RNASE L DNA Polymerases RNA Polymerases Helicases DNA Ligase

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nNOS iNOS eNOS

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Description

anti-TNBC agent-12 (Compound 23a) is a multi-target antitumor agent targeting HDAC6 (IC50=30.3 nM), DNA, and inducing nitric oxide (NO) release. anti-TNBC agent-12 induces tumor cell apoptosis and G2/M phase cell cycle arrest. anti-TNBC agent-12 is promising for research of triple-negative breast cancer (TNBC)[1].

Molecular Weight

628.61

Formula

C30H24N6O8S
SMILES

O=S(C1=CC=CC=C1)(C2=[N+]([O-])ON=C2OCCNC(C3=CC(C(C=CC=C4)=C4N5CC6=CC=C(C(NO)=O)C=C6)=C5C=N3)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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anti-TNBC agent-12 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

anti-TNBC agent-12HDACDNA/RNA SynthesisNO SynthaseApoptosisHistone deacetylasesNitric oxide synthasesNOSHDAC6DNANOInhibitorinhibitorinhibit

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anti-TNBC agent-12
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HY-178487
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