Free Radical Scavengers
Free radical scavengers are bioactive substances that eliminate reactive free radicals. Free radicals with unpaired electrons easily damage lipids, proteins and DNA, causing oxidative stress and cell aging.
Free radical scavengers neutralize radicals by donating electrons or hydrogen atoms to form stable inert compounds. Their scavenging capacity is measured by in vitro assays including DPPH and ABTS tests.
Common natural scavengers are polyphenols, flavonoids, vitamin C and vitamin E. They are widely studied for food preservation, cosmetic anti-oxidation and treatments for oxidative damage-related diseases.
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Free Radical Scavengers Verwandte Produkte (379)
Verwandte Produkte (379)
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Ferroptosis-IN-25
0 ImagesArt. -Nr.: HY-183289Ferroptosis-IN-25, Trolox (HY-101445) derivative, is a selective ferroptosis inhibitor. Ferroptosis-IN-25 selectively inhibits ferroptosis by scavenging ROS and suppressing lipid peroxidation independently of glutathion. Ferroptosis-IN-25 reduces corneal neovascularization and edema in murine corneal alkali burn models via topical administration.Ferroptosis-IN-25 can be used for the research of ocular surface diseases.
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PQM-164
0 ImagesArt. -Nr.: HY-159152CAS. Nr.: 2226535-25-5PQM-164 (Compound 3e) has antioxidant activity (IC50: 0.93 μM for DPPH radical). PQM-164 shows anti-inflammatory activity against 6-OHDA (HY-B1081A)-induced neuronal damage in activated microglial cells. PQM-164 decreases the accumulation of α-synuclein. PQM-164 promotes nuclear translocation of Nrf2 and its transcriptional activity. PQM-164 can be used for research of Parkinson’s disease.
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TAN-420E
0 ImagesArt. -Nr.: HY-W747504CAS. Nr.: 91700-93-5Synonyms: Dihydroherbimycin ATAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC50 of 1.3 μM.
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Anhydroevoxine
0 ImagesArt. -Nr.: HY-N17362CAS. Nr.: 24099-25-0Anhydroevoxine is a furoquinoline alkaloid that can be found in Vepris glomerata. Anhydroevoxine demonstrates in vitro antioxidant activity, reducing Fe3+ to Fe2+ and scavenging DPPH radicals.
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Evariquinone
0 ImagesArt. -Nr.: HY-118817CAS. Nr.: 594860-23-8Evariquinone is an anthraquinone compound isolated from the endophytic fungus Colletotrichum sp. JS-0367 of mulberry. Evariquinone possesses direct antioxidant activity. It inhibits excessive phosphorylation of the JNK, ERK1/2 and p38 MAPK signaling pathways by suppressing ROS and Ca2+, thereby reducing neuronal apoptosis. Evariquinone can be used to study glutamate excitotoxicity-related neurological disorders (such as Alzheimer's disease, Parkinson's disease, cerebral ischemia, etc.).
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Laricitrin 3-O-glucoside
0 ImagesArt. -Nr.: HY-N7904CAS. Nr.: 39986-90-8Laricitrin 3-O-glucoside is an antioxidant agent. Laricitrin 3-O-glucoside correlates significantly with DPPH assay and CUPRAC assay.
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Eleocharin B
0 ImagesArt. -Nr.: HY-N21601CAS. Nr.: 1619976-97-4Eleocharin B is a prenylated flavanone antioxidant and DPPH free radical scavenger. Eleocharin B is obtained from the peel of Eleocharis tuberosa (water chestnut). Eleocharin B is used in the study of oxidative stress-related disorders.
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Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside
0 ImagesArt. -Nr.: HY-N9368CAS. Nr.: 52714-82-6Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside is a flavonoid with antiradical activity.
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6-O-Acetylacteoside
0 ImagesArt. -Nr.: HY-N18355CAS. Nr.: 441769-43-3Synonyms: 6-O-Acetylact6-O-Acetylacteoside (6-O-Acetylact) is a Acteoside (HY-N0021) analog. 6-O-Acetylacteoside can scavenge radical.
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A2AAR antagonist 5
0 ImagesArt. -Nr.: HY-175851A2AAR antagonist 5 is a selective A2AAR antagonist. A2AAR antagonist 5 inhibits NECA-stimulated adenylyl cyclase activity in hA2AAR-expressing CHO cells with an IC50 value of 1863 nM. A2AAR antagonist 5 possesses strong free radical scavenging activity, with an EC50 value of 22.21 μM in the DPPH assay. A2AAR antagonist 5 exerts notable neuroprotective effects in in vitro cerebral ischemia models. A2AAR antagonist 5 can be used for the study of cerebral ischemia.
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Urease-IN-14
0 ImagesArt. -Nr.: HY-W357738CAS. Nr.: 74901-20-5
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Sigmoidin B
0 ImagesArt. -Nr.: HY-N11845CAS. Nr.: 87746-47-2Sigmoidin B, a prenylated flavanone, is a selective 5-lipoxygenase inhibitor. Sigmoidin B is a potent scavenger of the DPPH radical. Sigmoidin B has antigenotoxic activity that inhibits genotoxicity induced by Aflatoxin B1 (HY-N6615), with an IC50 of 18.7 μg/mL. Sigmoidin B has anti-inflammatory activity and antioxidant properties.
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Tetrahydroauroglaucin
0 ImagesArt. -Nr.: HY-N10284CAS. Nr.: 40434-07-9Tetrahydroauroglaucin is a member of hydroquinones, with antioxidative effects.
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Tyrosinase-IN-19
0 ImagesArt. -Nr.: HY-157124Tyrosinase-IN-19 (compound 9) is a competitive tyrosinase inhibitor. Tyrosinase-IN-19 has strong antioxidant activities against ROS, ABTS+, and DPPH radicals. Tyrosinase-IN-19 suppresses tyrosinase expression in a dose-dependent manner.
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5-Hydroxynoracronycine
0 ImagesArt. -Nr.: HY-N16745CAS. Nr.: 27067-70-55-Hydroxynoracronycine is a selective inhibitor targeting Leishmania, HIV-1 protease, and nitric oxide (NO) production. 5-Hydroxynoracronycine has an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for scavenging DPPH free radicals. 5-Hydroxynoracronycine exerts anti-leishmanial, anti-HIV, antioxidant and antibacterial activities by inhibiting pathogen proliferation, enzyme activity and inflammation-related NO excessive production. 5-Hydroxynoracronycine can be used in the research of leishmaniasis, HIV infection, and inflammation-related diseases.
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Hexadecyl ferulate
0 ImagesArt. -Nr.: HY-N21799CAS. Nr.: 64190-80-3Hexadecyl ferulate is a lipophilic C16 alkyl ferulate synthesized from ferulic acid and cetyl alcohol, possessing free radical-scavenging antioxidant activity. Hexadecyl ferulate inhibits the formation of lipid oxidation products in soybean oil during deep frying and exhibits antioxidant efficacy that increases with alkyl chain length. Hexadecyl ferulate can be used in antioxidant-related research.
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Pim-1 kinase inhibitor 4
0 ImagesArt. -Nr.: HY-149976CAS. Nr.: 3026670-71-0Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor (IC50: 17.01 nM). Pim-1 kinase inhibitor 4 also has antioxidant activity and inhibits DPPH. Pim-1 kinase inhibitor 4 induces apoptosis in PC-3 cell, and inhibits PC-3 cell growth with an IC50 of 16 nM. Pim-1 kinase inhibitor 4 can be used for research of prostate cancer.
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AChE-IN-112
0 ImagesArt. -Nr.: HY-182333AChE-IN-112 is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.41 μM. AChE-IN-112 scavenges various reactive oxygen and reactive nitrogen species, including DPPH, ABTS, NO, hydroxyl and hydrogen peroxide free radicals. AChE-IN-112 can be used for the research of Alzheimer's disease.
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Antioxidant agent-10
0 ImagesArt. -Nr.: HY-N11655CAS. Nr.: 1181635-91-5Antioxidant agent-10 (Compound 3) is an antioxidant agent that exhibits moderate DPPH scavenging activity with an EC50 of 33.2 μg/mL.
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Talienbisflavan A
0 ImagesArt. -Nr.: HY-N21650CAS. Nr.: 1412458-47-9Talienbisflavan A is a free radical scavenger found in green tea made from the leaves of Camellia taliensis. Talienbisflavan A mediates DPPH radical scavenging activity. Talienbisflavan A mediates ABTS+ radical scavenging activity. Talienbisflavan A exhibits antioxidant activity.
