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Art. -Nr.: HY-N20729

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Eucommin A

Eucommin A is a natural polyphenolic antioxidant. Eucommin A forms stable complexes with EGFR and MAPK8 via hydrogen bonding and hydrophobic interactions, and regulates osteoarthritis-related Autophagy. Eucommin A is applicable to research related to oxidative stress, such as osteoarthritis.

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CAS. Nr.: 99633-12-2
Formel: C₂₇H₃₄O₁₂
Molecular Weight:550.56

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eucommin A Chemical Structure

CAS. Nr.: 99633-12-2

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle EGFR Isoform-spezifische Produkte anzeigen :

Alle p38 MAPK Isoform-spezifische Produkte anzeigen :

In Vitro

Eucommin A binds tightly to purified human EGFR protein and human MAPK8 protein via multiple hydrogen bonds, with binding energies of -7.8 kcal/mol and -9.1 kcal/mol^[1].
Eucommin A is a polyphenolic component with in vitro antioxidant activity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 99633-12-2
Molecular Weight 550.56
Formel C₂₇H₃₄O₁₂
SMILES

O(C)C=1C=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C4=CC(OC)=C(O)C=C4)(CO2)[H])[H])C=C(OC)C1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Yage Zhang, et al. Bioinformatics-based identification of autophagy-related key genes in osteoarthritis and therapeutic potential analysis of Eucommin A[J]. Journal of Chinese Pharmaceutical Sciences, 2025, 34(9): 831-849.

[2]. Boubertakh H, et al. RP-UHPLC-ESI-QTOF-MSⁿ analyses, antioxidant, antimicrobial, analgesic activities and toxicity of Achillea ligustica All. Natural Product Research, 2025, 39(11): 3316-3321.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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Eucommin A

Alle EGFR Isoform-spezifische Produkte anzeigen

Alle p38 MAPK Isoform-spezifische Produkte anzeigen