Eugenol-d3
Based on 1 Customer Validation
Eugenol-d3 is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
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- Reinheit: 98.52%
- CAS. Nr.: 1335401-17-6
- Formel: C10H9D3O2
- Molecular Weight:167.22
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1335401-17-6
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Unlabeled Cas 97-53-0
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Appearance Liquid
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Molecular Weight 167.22
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Formel C10H9D3O2
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Color Colorless to light yellow
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SMILES
[2H]C([2H])([2H])OC1=CC(CC=C)=CC=C1O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (598.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Pessoa LM, et al. Anthelmintic activity of essential oil of Ocimum gratissimum Linn. and eugenol against Haemonchus contortus. Vet Parasitol. 2002 Oct 16;109(1-2):59-63. [Content Brief]
[3]. Reddy AC, et al. Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygenspecies and the oxidation of ferrous iron. Mol Cell Biochem. 1994 Aug 17;137(1):1-8. [Content Brief]
[4]. Garabadu D, et al. Protective effect of eugenol against restraint stress-induced gastrointestinal dysfunction: Potential use in irritable bowel syndrome. Pharm Biol. 2015 Jul;53(7):968-74. [Content Brief]
[5]. Sharma JN, et al. Suppressive effects of eugenol and ginger oil on arthritic rats. Pharmacology. 1994 Nov;49(5):314-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.9801 mL | 29.9007 mL | 59.8015 mL | 149.5036 mL |
| 5 mM | 1.1960 mL | 5.9801 mL | 11.9603 mL | 29.9007 mL | |
| 10 mM | 0.5980 mL | 2.9901 mL | 5.9801 mL | 14.9504 mL | |
| 15 mM | 0.3987 mL | 1.9934 mL | 3.9868 mL | 9.9669 mL | |
| 20 mM | 0.2990 mL | 1.4950 mL | 2.9901 mL | 7.4752 mL | |
| 25 mM | 0.2392 mL | 1.1960 mL | 2.3921 mL | 5.9801 mL | |
| 30 mM | 0.1993 mL | 0.9967 mL | 1.9934 mL | 4.9835 mL | |
| 40 mM | 0.1495 mL | 0.7475 mL | 1.4950 mL | 3.7376 mL | |
| 50 mM | 0.1196 mL | 0.5980 mL | 1.1960 mL | 2.9901 mL | |
| 60 mM | 0.0997 mL | 0.4983 mL | 0.9967 mL | 2.4917 mL | |
| 80 mM | 0.0748 mL | 0.3738 mL | 0.7475 mL | 1.8688 mL | |
| 100 mM | 0.0598 mL | 0.2990 mL | 0.5980 mL | 1.4950 mL |
Eugenol-d3 Related Classifications
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