IR-251
IR-251 is a mitochondrion-targeting NIR fluorescent probe. IR-251 targets mitochondria via OATPs and causes mitochondrial damage in tumor cells. IR-251 IR-251 induced ROS overproduction by inhibiting PPARγ, and then inhibiting the β-catenin signaling pathway and downstream protein molecules related to the cell cycle and metastasis. IR-251 inhibits tumor proliferation and metastasis.
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- Formel: C51H70BrClN4O2
- Molecular Weight:886.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biologische Aktivität
Chemical Information
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Molecular Weight 886.48
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Formel C51H70BrClN4O2
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SMILES
CC1(C)C(/C=C/C2=C(Cl)/C(CCC2)=C/CC3N(CCCCCC(O/C(NC4CCCCC4)=N/C5CCCCC5)=O)C(C=CC=C6)=C6C3(C)C)=[N+](CC)C7=C1C=CC=C7.[Br-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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