OPB-3206
OPB-3206 is a selective matrix metalloproteinase (MMP) inhibitor. OPB-3206 inhibits interstitial collagenase, gelatinase A (MMP-2), gelatinase B (MMP-9) and stromelysin with IC50 values of 7×10-7 M, 5×10-6 M, 5×10-7 M and 2×10-6 M, respectively. OPB-3206 reversibly binds to the zinc-binding region of MMPs, preventing the activation of MMP-9 and reducing extracellular matrix degradation to inhibit tumor lung metastasis. OPB-3206 is promising for research of lung metastasis of osteosarcoma.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 166245-54-1
- Formel: C18H25N3O5
- Molecular Weight:363.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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MMP-2 5 μM (IC50) |
MMP-9 0.5 μM (IC50) |
Chemical Information
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CAS. Nr. 166245-54-1
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Molecular Weight 363.41
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Formel C18H25N3O5
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SMILES
CON1C2=CC=CC=C2C[C@@H](C1=O)NC([C@H](CC(C)C)CC(NO)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
OPB-3206 Related Classifications
HY-171776 Related Classifications
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