Art. -Nr.: HY-B0351

Taurine

(Synonyms: 2-Aminoethanesulfonic acid)

20 Cited Publications

Kundenbewertung

Based on 20 publication(s) in Google Scholar

Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.

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Reinheit: 99.99%
CAS. Nr.: 107-35-7
Formel: C₂H₇NO₃S
Molecular Weight:125.15

Speicherung:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Taurine Chemical Structure

CAS. Nr.: 107-35-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
- Clinical Trial
Chemical Information
Publications (20)
Lösungsmittel & Löslichkeit
- In Vitro
- In Vivo
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

Human Endogenous Metabolite

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	10 μM Compound: 1123	Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells	10.5281/zenodo.7360560
HEK293	EC₅₀	10 μM Compound: 1123	Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells (PubChem AID: 1794824) Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells (PubChem AID: 1794824)	10.5281/zenodo.7360560
L6	IC₅₀	>90 μg/mL Compound: 6	Cytotoxicity against rat L6 cells after 72 hrs Cytotoxicity against rat L6 cells after 72 hrs	[PMID: 17765547]

In Vitro

Taurine is one of the most abundant amino acids in the brain and spinal cord, leukocytes, heart and muscle cells, the retina, and indeed almost every tissue throughout the body^[1].
Taurine exhibits diverse biological actions, including protection against ischemia-reperfusion injury, modulation of intracellular calcium concentration, and antioxidant, antiatherogenic and blood pressure-lowering effects^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS. Nr. 107-35-7
Appearance Solid
Molecular Weight 125.15
Formel C₂H₇NO₃S
Color White to off-white
SMILES

NCCS(=O)(O)=O
Synonyms

2-Aminoethanesulfonic acid
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Publications (20)

All Cell Proliferation/Viability AssayIn Vivo Efficacy StudyWB

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Journal Impact Factor

Cell Res

Structural basis of augmenting taurine uptake by the taurine transporter in alleviating cellular senescence. [Abstract]

2025 May;35(5):385-388. PMID: 40108449
Cell Host Microbe

Microbiota-derived urocanic acid triggered by tyrosine kinase inhibitors potentiates cancer immunotherapy efficacy. [Abstract]

2025 Jun 11;33(6):915-931.e9. PMID: 40441145
Nat Commun

Btg2 inhibits Fmo1 UFMylation thus exacerbating ferroptosis and apoptosis in hepatic ischemia-reperfusion injury. [Abstract]

2026 May 9. PMID: 42106354
J Adv Res

Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging. [Abstract]

2024 May 7:S2090-1232(24)00183-8. PMID: 38718895
Adv Sci (Weinh)

Single-Cell Simultaneous Metabolome and Transcriptome Profiling Revealing Metabolite-Gene Correlation Network. [Abstract]

2024 Dec 4:e2411276. PMID: 39629980
J Transl Med

Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine. [Abstract]

2025 Oct 15;23(1):1106. PMID: 41094491
EMBO J

The NLRP6 inflammasome is activated by sterile or pathogen-induced endolysosomal damage. [Abstract]

2025 Nov 20. PMID: 41266655

Taurine purchased from MedChemExpress. Usage Cited in: EMBO J. 2025 Nov 20. [Abstract]

LDH release from NLRP6-WT^tg HIEC-6 cells induced or not with 1 μg/ml doxycycline overnight and infected with WT or Δhly L. monocytogenes EGD for 8 h or treated with 70 mM Taurine.
Free Radic Biol Med

Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing. [Abstract]

2025 Apr 3:S0891-5849(25)00207-2. PMID: 40187503

Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Apr 3:S0891-5849(25)00207-2. [Abstract]

CCK-8 assay assessing PC12 cell viability after Taurine (TA, 40-120 mM; 24-72 h) treatment at various concentrations for 24 h (A), 48 h (B), and 72 h (C).
Free Radic Biol Med

Taurine attenuates neuronal ferroptosis by regulating GABAB/AKT/GSK3β/β-catenin pathway after subarachnoid hemorrhage. [Abstract]

2022 Nov 20;193(Pt 2):795-807. PMID: 36402441

Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807. [Abstract]

Taurine (400 mg/kg; i.p. 30 min before and 12 h after SAH). Bar graphs showed mortality rates at 24 h after subarachnoid hemorrhage (SAH) in mice.

Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807. [Abstract]

Taurine (400 mg/kg; i.p. 30 min before and 12 h after SAH). Western blotting images and quantitative data of relative expression level of ZO-1 and occludin in cerebral cortex at 24 h after subarachnoid hemorrhage (SAH) (n = 4/group).

Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807. [Abstract]

The viability of HT22 treated by different concentration of Taurine (5-20 mM) for 24 h was tested by CCK-8 assay in vitro (n = 6/group).
PLoS Biol

A high-throughput behavioral screening platform for measuring chemotaxis by C. elegans. [Abstract]

2024 Jun 27;22(6):e3002672. PMID: 38935621
Eur J Pharmacol

Taurine ameliorates liver fibrosis by repressing Fpr2-regulated macrophage M1 polarization. [Abstract]

2025 Apr 9:177614. PMID: 40216178
Front Cell Dev Biol

Taurine Attenuates the Hypotaurine-Induced Progression of CRC via ERK/RSK Signaling. [Abstract]

2021 Apr 15:9:631163. PMID: 33937232
Sci Rep

Taurine stimulates EPO production in feline renal cells through the HIF pathway. [Abstract]

2026 Apr 9;16(1):16713. PMID: 41957466
FASEB J

Protective Effects of Taurine Against Zearalenone-Induced Quality Impairment During Porcine Oocyte Maturation. [Abstract]

2026 Jun 30;40(12):e72072. PMID: 42333697
Clin Chim Acta

SAH and SAM/SAH ratio associate with acute kidney injury in critically ill patients: A case-control study. [Abstract]

2024 Jan 15:553:117726. PMID: 38110027
Microbiol Spectr

Disruption of the Intestinal Mucosal Barrier Induced by High Fructose and Restraint Stress Is Regulated by the Intestinal Microbiota and Microbiota Metabolites. [Abstract]

2023 Jan 31;11(2):e0469822. PMID: 36719201
PLoS One

Taurine is a potential therapy for rheumatoid arthritis via targeting FOXO3 through cellular senescence and autophagy. [Abstract]

2025 Apr 16;20(4):e0318311. PMID: 40238799
World J Gastrointest Oncol

Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a -/- mice. [Abstract]

2026 Feb 15;18(2):114161. PMID: 41695925
bioRxiv

2024 November 14.
bioRxiv

An efficient behavioral screening platform classifies natural products and other chemical cues according to their chemosensory valence in C. elegans. [Abstract]

2024 Apr 3:2023.06.02.542933. PMID: 37333363

Lösungsmittel & Löslichkeit

In Vitro:

H₂O : 25 mg/mL (199.76 mM; Need ultrasonic)

DMSO : 1 mg/mL (7.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

7.9904 mL

39.9521 mL

79.9041 mL

5 mM

1.5981 mL

7.9904 mL

15.9808 mL

10 mM

0.7990 mL

3.9952 mL

7.9904 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

In Vivo:

Working Solution

For the following dissolution methods, please prepare the working solution directly:

It is recommended to prepare fresh solutions and use them promptly within a short period of time.

The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS

Solubility: 12.5 mg/mL (99.88 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ripps H, Shen W. Review: taurine: a "very essential" amino acid. Mol Vis. 2012;18:2673-2686. [Content Brief]

[2]. Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65. [Content Brief]

[3]. Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50(5):527-535. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO / H₂O	1 mM	7.9904 mL	39.9521 mL	79.9041 mL	199.7603 mL
DMSO / H₂O	5 mM	1.5981 mL	7.9904 mL	15.9808 mL	39.9521 mL
H₂O	10 mM	0.7990 mL	3.9952 mL	7.9904 mL	19.9760 mL
	15 mM	0.5327 mL	2.6635 mL	5.3269 mL	13.3174 mL
	20 mM	0.3995 mL	1.9976 mL	3.9952 mL	9.9880 mL
	25 mM	0.3196 mL	1.5981 mL	3.1962 mL	7.9904 mL
	30 mM	0.2663 mL	1.3317 mL	2.6635 mL	6.6587 mL
	40 mM	0.1998 mL	0.9988 mL	1.9976 mL	4.9940 mL
	50 mM	0.1598 mL	0.7990 mL	1.5981 mL	3.9952 mL
	60 mM	0.1332 mL	0.6659 mL	1.3317 mL	3.3293 mL
	80 mM	0.0999 mL	0.4994 mL	0.9988 mL	2.4970 mL
	100 mM	0.0799 mL	0.3995 mL	0.7990 mL	1.9976 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Keywords

Taurine

20 Cited Publications

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Publications Citing Use of MedChemExpress (MCE) Taurine

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (20)

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Taurine Related Classifications

HY-B0351 Related Classifications