Thalidomide-5-methanol
Thalidomide-5-methanol is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-5-methanol can be linked to a target protein ligand via a linker to form a PROTAC.
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- CAS. Nr.: 2825006-38-8
- Formel: C14H12N2O5
- Molecular Weight:288.26
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 2825006-38-8
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Molecular Weight 288.26
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Formel C14H12N2O5
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SMILES
O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)CO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Thalidomide-5-methanol Related Classifications
HY-W586327 Related Classifications
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