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EP009

EP009 is a JAK3 inhibitor that selectively inhibits IL-2-mediated JAK3 tyrosine phosphorylation (IC50=10-20 μM in Kit225 cells) without affecting IL-3-induced JAK2 phosphorylation (up to 50 μM in BaF/3 cells). EP009 significantly reduced Kit225 cell viability (72 h, LD50=5.0 μM) while having no effect on BaF/3 cells..

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  • CAS No.: 1462951-30-9
  • Formula: C14H24O2
  • Molecular Weight:224.34
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EP009 Chemical Structure
    EP009 Chemical Structure
CAS No.: 1462951-30-9
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All JAK Isoforms

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  • EP009 Chemical Structure
    EP009 Chemical Structure
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  • EP009