1. Epigenetics
  2. Epigenetic Reader Domain
  3. ODM-207

ODM-207  (Synonyms: BET-IN-4)

Cat. No.: HY-111916 Purity: 99.71%
COA Handling Instructions

ODM-207 (BET-IN-4) is a potent BET bromodomain protein (BRD4) inhibitor, with an IC50 of ≤ 1 μM.

For research use only. We do not sell to patients.

ODM-207 Chemical Structure

ODM-207 Chemical Structure

CAS No. : 1801503-93-4

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 198 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 198 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
10 mg USD 290 In-stock
Estimated Time of Arrival: December 31
25 mg USD 580 In-stock
Estimated Time of Arrival: December 31
50 mg USD 920 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1480 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

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Description

ODM-207 (BET-IN-4) is a potent BET bromodomain protein (BRD4) inhibitor, with an IC50 of ≤ 1 μM[1].

IC50 & Target[1]

BRD4

≤ 1 μM (IC50)

In Vitro

ODM-207 (Compound 50) is a potent BET bromodomain protein (BRD4) inhibitor, with an IC50 of ≤ 1 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

375.42

Formula

C22H21N3O3

CAS No.
SMILES

O=C1N(CC2=NC=CC=C2)C3=C(C=C(C4=C(C)ON=C4C)C(OC)=C3)C=C1C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (26.64 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6637 mL 13.3184 mL 26.6368 mL
5 mM 0.5327 mL 2.6637 mL 5.3274 mL
10 mM 0.2664 mL 1.3318 mL 2.6637 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.83 mg/mL (2.21 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.83 mg/mL (2.21 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 0.83 mg/mL (2.21 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
ODM-207
Cat. No.:
HY-111916
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