BLI-489
Based on 1 Customer Validation
BLI-489 is a beta-lactamase inhibitor. BLI-489 combined with Piperacillin (HY-B1923) inhibits infection caused by class A (including ultra-broad spectrum β-lactamase), Class C (AmpC) and Class D β-lactamase expressing pathogens.
For research use only. We do not sell to patients.
- Purity: 95.77%
- CAS No.: 623564-40-9
- Formula: C13H10N3NaO4S
- Molecular Weight:327.29
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Beta-lactamase Isoforms
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 623564-40-9
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Appearance Solid
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Molecular Weight 327.29
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Formula C13H10N3NaO4S
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Color Light yellow to yellow
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SMILES
O=C(C1=CS[C@@](/C2=C/C3=CN4C(COCC4)=N3)([H])N1C2=O)O[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 105 mg/mL (320.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0554 mL | 15.2770 mL | 30.5539 mL | 76.3849 mL |
| 5 mM | 0.6111 mL | 3.0554 mL | 6.1108 mL | 15.2770 mL | |
| 10 mM | 0.3055 mL | 1.5277 mL | 3.0554 mL | 7.6385 mL | |
| 15 mM | 0.2037 mL | 1.0185 mL | 2.0369 mL | 5.0923 mL | |
| 20 mM | 0.1528 mL | 0.7638 mL | 1.5277 mL | 3.8192 mL | |
| 25 mM | 0.1222 mL | 0.6111 mL | 1.2222 mL | 3.0554 mL | |
| 30 mM | 0.1018 mL | 0.5092 mL | 1.0185 mL | 2.5462 mL | |
| 40 mM | 0.0764 mL | 0.3819 mL | 0.7638 mL | 1.9096 mL | |
| 50 mM | 0.0611 mL | 0.3055 mL | 0.6111 mL | 1.5277 mL | |
| 60 mM | 0.0509 mL | 0.2546 mL | 0.5092 mL | 1.2731 mL | |
| 80 mM | 0.0382 mL | 0.1910 mL | 0.3819 mL | 0.9548 mL | |
| 100 mM | 0.0306 mL | 0.1528 mL | 0.3055 mL | 0.7638 mL |
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