1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. Bropirimine

Bropirimine 

Cat. No.: HY-W008634
Handling Instructions

Bropirimine is a synthetic agonist for toll-like receptor 7 (TLR7). Bropirimine inhibits differentiation of osteoclast precursor cells into osteoclasts via TLR7-mediated production of IFN-β. Bropirimine is an orally active immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in situ (CIS) in both the bladder and upper urinary tract.

For research use only. We do not sell to patients.

Bropirimine Chemical Structure

Bropirimine Chemical Structure

CAS No. : 56741-95-8

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Description

Bropirimine is a synthetic agonist for toll-like receptor 7 (TLR7). Bropirimine inhibits differentiation of osteoclast precursor cells into osteoclasts via TLR7-mediated production of IFN-β. Bropirimine is an orally active immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in situ (CIS) in both the bladder and upper urinary tract[1][2].

Molecular Weight

266.09

Formula

C₁₀H₈BrN₃O

CAS No.

56741-95-8

SMILES

O=C1NC(N)=NC(C2=CC=CC=C2)=C1Br

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

BropirimineToll-like Receptor (TLR)antitumourimmunostimulantdifferentiationcarcinomaurinarytractInhibitorinhibitorinhibit

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Bropirimine
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