- Recombinant Proteins
- CD Antigens
- B Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins Dendritic Cell CD Proteins
- CD20
CD20
CD20 is a tetraspanin-like membrane protein, encoded by the MS4A1 gene, found almost exclusively on B lymphocytes from the pre-B-cell stage until plasma-cell differentiation. The protein forms oligomeric calcium channels that help sustain intracellular calcium stores required for B-cell receptor signaling and activation. Because CD20 is neither shed nor internalized appreciably and is absent from stem cells and plasma cells, it became the premier target for B-cell depleting antibodies; rituximab, ofatumumab and obinutuzumab treat lymphomas, leukemias and autoimmune diseases, while anti-CD20 CAR T cells address relapsed disease. CD20 is also a defining marker in B-cell lymphoma pathology.
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CD20 Recombinant Proteins (14)
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- 1
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
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