8CN
8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis.
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- CAS No.: 40106-14-7
- Formule: C11H14N2S
- Masse moléculaire:206.31
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Leishmania |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| J774.A1 | CC50 |
43.9 μM
Compound: 8CN
|
Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay
Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay
|
[PMID: 36848847] |
8CN (72 h) has anti-leishmanial activity against the two evolutionary forms of Leishmania amazonensis (amastigotes and promastigotes) with IC50 values of 9.8 and 1.2 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 40106-14-7
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Masse moléculaire 206.31
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Formule C11H14N2S
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SMILES
C1CCCC2=C(CC1)C(=C(N)S2)C#N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)