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NSC 23766

55 Cited Publications
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Based on 55 publication(s) in Google Scholar

NSC 23766 is a cell-permeable, reversible and specific inhibitor of Rac GTPase, used for cancer treatment.

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  • Pureté: 99.86%
  • CAS No.: 733767-34-5
  • Formule: C24H35N7
  • Masse moléculaire:421.58
  • Stockage:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • NSC 23766 Chemical Structure
    NSC 23766 Chemical Structure
  • Experimental Validation Results for NSC 23766
  • Experimental Validation Results for NSC 23766
  • Experimental Validation Results for NSC 23766
  • Experimental Validation Results for NSC 23766
  • Experimental Validation Results for NSC 23766
CAS No.: 733767-34-5
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  • NSC 23766 Chemical Structure
    NSC 23766 Chemical Structure
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    NSC 23766 purchased from MedChemExpress. Usage Cited in: Cell Rep. 2025 Dec 6;44(12):116649. [Abstract]

    Customer Validation
     Single WT and RHOA-KO HEK293 cells were seeded in Geltrex and cultured for 4 days in the presence of 10 μM NSC-23766.

  • 1/16

    NSC 23766 purchased from MedChemExpress. Usage Cited in: Nat Metab. 2022 Dec;4(12):1830-1846. [Abstract]

    Customer Validation
     NSC23766 (NSC; 1.5 mg/kg/day; i.p.) in combination with FX11(1 mg/kg/day; i.p.) for 2-3 weeks. The combination treatment displayed a much more pronounced inhibitory effect on lung metastasis of Hs578T cells than the single inhibitor treatment.

  • 1/16

    NSC 23766 purchased from MedChemExpress. Usage Cited in: Nat Metab. 2022 Dec;4(12):1830-1846. [Abstract]

    Customer Validation
     NSC23766 (NSC; 1.5 mg/kg/day; i.p.). The combination treatment displayed a much more pronounced inhibitory effect on lung metastasis of mammary tumors of MMTV-PyMT mice than the single inhibitor treatment.

  • 1/16

    NSC 23766 purchased from MedChemExpress. Usage Cited in: Nat Metab. 2022 Dec;4(12):1830-1846. [Abstract]

    Customer Validation
     NSC23766 (NSC; 1.5 mg/kg/day; i.p.). The combination treatment displayed a much more pronounced inhibitory effect on the growth of mammary tumors of MMTV-PyMT mice than the single inhibitor treatment.

  • 1/16

    NSC 23766 purchased from MedChemExpress. Usage Cited in: Arch Toxicol. 2022 Jul;96(7):2113-2122. [Abstract]

    Customer Validation
     Effect of glucose glycolysis on HETs induced by CPA. Heterophils were intervened with specific inhibitors NSC23766 (200 μM) for 30 min, then incubated for 90 min with CPA. HETs formation was quantified with PicoGreen.

  • NSC 23766