CD28-IN-1
CD28-IN-1 (Compound 19MS-5) is a CD28 inhibitor with a KD of 12.48 μM. CD28-IN-1 has a superior binding capacity to CD28 and potently inhibits CD28-B7 interactions. CD28-IN-1 inhibits CD28-driven immune activation and suppresses cytokine (IFN-γ, IL-2 and TNF-α) production in primary human T cells co-cultured with tumor spheroids and human epithelial tissues. CD28-IN-1 can be used for tumor immunity research.
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- CAS No.: 1465291-19-3
- Formule: C16H17N3O4
- Masse moléculaire:315.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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IL-2 |
Chemical Information
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CAS No. 1465291-19-3
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Masse moléculaire 315.32
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Formule C16H17N3O4
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SMILES
O=C1N(C)C2=CC=CC(C(OCCC3=C(C)NN=C3C)=O)=C2O1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CD28-IN-1 Related Classifications
HY-175780 Related Classifications
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