CUMI-101
CUMI-101 (compound 8) is a 5-HT1AR agonist (Ki=0.15 nM) with an EC50 of 0.1 nM in the [35S]GTPγS binding assay. CUMI-101 can be used in the research of neurological diseases.
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- CAS No.: 179756-61-7
- Formule: C19H27N5O3
- Masse moléculaire:373.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Voir tous les produits spécifiques à Isoform 5-HT Receptor
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
0.1 nM
Compound: 8, CUMI-101
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Agonist activity at human 5HT1AR expressed in CHO cells assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectrometry
Agonist activity at human 5HT1AR expressed in CHO cells assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectrometry
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[PMID: 25182564] |
| CHO | EC50 |
0.1 nM
Compound: CUMI-101
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Partial agonist activity at human 5HT1A receptor expressed in CHO cells assessed as increase in [35S]GTPgammaS binding
Partial agonist activity at human 5HT1A receptor expressed in CHO cells assessed as increase in [35S]GTPgammaS binding
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[PMID: 23816046] |
Chemical Information
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CAS No. 179756-61-7
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Masse moléculaire 373.45
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Formule C19H27N5O3
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SMILES
O=C(N(N=CC1=O)CCCCN2CCN(CC2)C3=CC=CC=C3OC)N1C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CUMI-101 Related Classifications
HY-116065 Related Classifications
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