DH-18
DH-18 is a matrix metalloproteinase-2 (MMP-2) inhibitor with the IC50 values of 139.45 nM, 518.11 nM and 833.34 nM for MMP-2, MMP-9 and MMP-8, respectively. DH-18 induces cell apoptosis and arrests cell cycle in the G0/G1 phase. DH-18 inhibits cell growth and can be used for study of chronic myeloid leukemia.
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- Formule: C26H23F6N3O5S
- Masse moléculaire:603.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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MMP-2 139.45 nM (IC50) |
MMP-9 518.11 nM (IC50) |
MMP-8 833.34 nM (IC50) |
Chemical Information
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Masse moléculaire 603.53
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Formule C26H23F6N3O5S
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SMILES
O=C(NCC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)CCC(C(NO)=O)NS(=O)(C2=CC=C(C=C2)C3=CC=CC=C3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)