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Cat. No.: HY-N20729

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Eucommin A

Eucommin A is a natural polyphenolic antioxidant. Eucommin A forms stable complexes with EGFR and MAPK8 via hydrogen bonding and hydrophobic interactions, and regulates osteoarthritis-related Autophagy. Eucommin A is applicable to research related to oxidative stress, such as osteoarthritis.

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CAS No.: 99633-12-2
Formule: C₂₇H₃₄O₁₂
Masse moléculaire:550.56

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Please store the product under the recommended conditions in the Certificate of Analysis.

Eucommin A Chemical Structure

CAS No.: 99633-12-2

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One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform EGFR :

Voir tous les produits spécifiques à Isoform p38 MAPK :

In Vitro

Eucommin A binds tightly to purified human EGFR protein and human MAPK8 protein via multiple hydrogen bonds, with binding energies of -7.8 kcal/mol and -9.1 kcal/mol^[1].
Eucommin A is a polyphenolic component with in vitro antioxidant activity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 99633-12-2
Masse moléculaire 550.56
Formule C₂₇H₃₄O₁₂
SMILES

O(C)C=1C=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C4=CC(OC)=C(O)C=C4)(CO2)[H])[H])C=C(OC)C1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Yage Zhang, et al. Bioinformatics-based identification of autophagy-related key genes in osteoarthritis and therapeutic potential analysis of Eucommin A[J]. Journal of Chinese Pharmaceutical Sciences, 2025, 34(9): 831-849.

[2]. Boubertakh H, et al. RP-UHPLC-ESI-QTOF-MSⁿ analyses, antioxidant, antimicrobial, analgesic activities and toxicity of Achillea ligustica All. Natural Product Research, 2025, 39(11): 3316-3321.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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- In Vitro
Chemical Information
Pureté et documentation
Références

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Eucommin A

Voir tous les produits spécifiques à Isoform EGFR

Voir tous les produits spécifiques à Isoform p38 MAPK