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Cat. No.: HY-W748000

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Kocurin

Name: Kocurin
Brand: MedChemExpress
SKU: HY-W748000
Availability: PreOrder

(Synonyms: PM181104; Baringolin)

Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria.

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CAS No.: 1374772-61-8
Formule: C₆₉H₆₆N₁₈O₁₃S₅
Masse moléculaire:1515.70

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Kocurin Chemical Structure

CAS No.: 1374772-61-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Antibiotic :

In Vitro

Kocurin (24 h) inhibits S. aureus with MICs in the range of 0.008 to 2.048 μg/mL and an MIC₉₀ value of 0.064 μg/mL^[1].
Kocurin (24 h) inhibits S. epidermidis with MICs in the range of 0.008 to 1.024 μg/mL and an MIC₉₀ value of 0.128 μg/mL^[1].
Kocurin (24 h) inhibits VRE and VSE strains with MICs in the range of 0.004 to 1.024 μg/mL and an MIC₉₀ value of 0.016 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Kocurin (1.25-10 mg/kg; intravenous injection; single dose) has the 100% effective dose (ED₁₀₀) values of 2.5 and 5.0 mg/kg for MRSA, and an ED₁₀₀ value of 10.0 mg/kg for VRE in the BALB/c mouse septicemia model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 1374772-61-8
Masse moléculaire 1515.70
Formule C₆₉H₆₆N₁₈O₁₃S₅
Synonyms

PM181104; Baringolin
Structure Classification
- Peptides
- Extract
Initial Source
- Marine natural products
- Sponge
- Microorganism
Micrococcus spp.
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (291 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mahajan G, et al. In vitro and in vivo activities of antibiotic PM181104. Antimicrob Agents Chemother. 2013 Nov;57(11):5315-9. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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